Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727716 | 0.93 | LMNA (0.36) | HPGDALDH1A1TDP1HSD17B10PDK2 | |
| SCHEMBL11766016 | 0.82 | ALDH1A1 (0.45) | HPGDALDH1A1TDP1HSD17B10PDK2 | |
| SCHEMBL179720 | 0.77 | FTO (0.49) | HPGDALDH1A1TDP1HSD17B10PDK2 | |
| SCHEMBL418120 | 0.76 | MAPT (0.42) | HPGDALDH1A1TDP1HSD17B10PDK2 | |
| SCHEMBL29722 | 0.74 | CHRM3 (0.46) | TDP1MEN1KMT2ACYP2C19P2RX1 | |
| SCHEMBL5475178 | 0.69 | PDK2 (0.38) | ALDH1A1PDK2KMT2AOPRL1MAPT | |
| SCHEMBL13871201 | 0.69 | CA12 (0.39) | ALDH1A1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL841189 | 0.69 | ALDH1A1 (0.37) | HPGDALDH1A1TDP1HSD17B10PDK2 | |
| SCHEMBL9610878 | 0.69 | FTO (0.66) | HPGDALDH1A1TDP1HSD17B10CYP3A4 | |
| SCHEMBL31580046 | 0.69 | FTO (0.66) | HPGDALDH1A1TDP1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249321-A1 | Fluorescent Probes | Nagano, Tetsuo (JP) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249321-A1 | Fluorescent Probes | CBR3, CBR1, SQOR | HPGD 2045/4885ALDH1A1 1415/4885TDP1 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.