Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240028 | 0.92 | FTO (0.45) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL18240021 | 0.88 | ALDH1A1 (0.30) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL8508597 | 0.82 | FTO (0.34) | ALDH1A1HPGDTDP1MEN1KMT2A | |
| SCHEMBL30360806 | 0.80 | PSMB5 (0.31) | — | |
| SCHEMBL29558140 | 0.80 | MAOA (0.43) | SLC6A4LMNA | |
| SCHEMBL11687105 | 0.79 | LMNA (0.45) | ALDH1A1HPGDTDP1SLC6A4PDK2 | |
| SCHEMBL3794922 | 0.79 | FTO (0.54) | ALDH1A1HPGDTDP1HSD17B10MEN1 | |
| SCHEMBL31376332 | 0.79 | LMNA (0.45) | ALDH1A1HPGDTDP1SLC6A4PDK2 | |
| SCHEMBL18240031 | 0.79 | FTO (0.43) | ALDH1A1HPGDTDP1CYP3A4HSD17B10 | |
| SCHEMBL16924017 | 0.79 | CA12 (0.39) | ALDH1A1HPGDTDP1CYP3A4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143069-B2 | useful for selective measurement of hypochlorite ion; does not react with hydrogen peroxide which is a weakly reactive oxygen species, and does not induce increase of fluorescence with hydroxyl radical or peroxynitrite which are reactive oxygen species having high activity | THE UNIVERSITY OF TOKYO (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20090317914-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090317914-A1 | FLUORESCENT PROBE | H1-10, H1-0, NHERF1 | ALDH1A1 1940/4885HPGD 3931/4885TDP1 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.