Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284185 | 0.98 | GLS (0.52) | GLSCASP3CA9CA1CA2 | |
| Potassium SCHEMBL6284198 | 0.98 | GLS (0.52) | GLSCASP3CA9CA1CA2 | |
| SCHEMBL918303 | 0.89 | TDP1 (0.51) | SMN1; SMN2RAB9ATDP1L3MBTL1MAPT | |
| SCHEMBL5372797 | 0.88 | CA9 (0.42) | GLSCASP3CA9CA1CA2 | |
| SCHEMBL2284215 | 0.87 | TDP1 (0.50) | SMN1; SMN2RAB9ATDP1L3MBTL1MAPT | |
| SCHEMBL2169798 | 0.87 | TDP1 (0.54) | TDP1L3MBTL1HDAC8HDAC3HDAC4 | |
| SCHEMBL3670226 | 0.87 | TDP1 (0.50) | SMN1; SMN2RAB9ATDP1L3MBTL1MAPT | |
| SCHEMBL17122199 | 0.86 | TDP1 (0.57) | SMN1; SMN2TDP1L3MBTL1HDAC8HPGD | |
| SCHEMBL5794366 | 0.86 | TDP1 (0.57) | SMN1; SMN2TDP1L3MBTL1HDAC8HPGD | |
| SCHEMBL19900766 | 0.86 | TDP1 (0.57) | SMN1; SMN2TDP1L3MBTL1HDAC8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578577-A1 | Sulfonyl esters of tetrahydrocannabinol and derivatives thereof | Albany Molecular Research, Inc. (US) | 2013-04-10 | — | — | EP | claimed |
| US-7674922-B2 | Process for production of delta-9-tetrahydrocannabinol | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-03-09 | — | — | US | claimed |
| EP-1928853-A2 | PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL | AMR Technology, Inc. (US) | 2008-06-11 | — | — | EP | claimed |
| US-20070093665-A1 | Process for production of delta-9- tetrahydrocannabinol | AMR TECHNOLOGY, INC. (US) | 2007-04-26 | — | — | US | claimed |
| WO-2007041167-A2 | PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL | AMR TECHNOLOGY, INC. (US) | 2007-04-12 | — | — | WO | claimed |
| US-9904167-B2 | Compound, active light sensitive or radiation sensitive resin composition, resist film using same, resist-coated mask blank, photomask, pattern forming method, method for manufacturing electronic device, and electronic device | FUJIFILM CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| US-20160185724-A1 | HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | FAB PHARMA (FR) | 2016-06-30 | — | — | US | disclosed |
| US-20160116840-A1 | COMPOUND, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, RESIST FILM USING SAME, RESIST-COATED MASK BLANK, PHOTOMASK, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2016-04-28 | — | — | US | disclosed |
| US-9309179-B2 | Hydroxyphenyl derivatives and biological applications thereof | FAB PHARMA (FR) | 2016-04-12 | — | — | US | disclosed |
| US-9242963-B2 | Organic compounds | NOVARTIS AG (CH) | 2016-01-26 | — | — | US | disclosed |
| US-20150210672-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2015-07-30 | — | — | US | disclosed |
| CN-104193725-A | ORGANIC COMPOUNDS | NOVARTIS AG | 2014-12-10 | — | — | CN | disclosed |
| US-20040058932-A1 | Novel piperazine derivatives | PFIZER INC. | 2004-03-25 | — | — | US | disclosed |
| US-6649611-B2 | Potent and selective inhibitors of chemokine binding to its receptor CCR1 found on inflammatory and immunomodulatory cells (preferably leukocytes and lymphocytes). | PFIZER, INC. | 2003-11-18 | — | — | US | disclosed |
| EP-1268455-A2 | PIPERAZINE DERIVATIVES | Pfizer Products Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072728-A9 | NOVEL PIPERAZINE DERIVATIVES | PFIZER PROD INC (US) | 2002-10-10 | — | — | WO | disclosed |
| US-20020107255-A1 | Novel piperazine derivatives | PFIZER PRODUCTS INC. | 2002-08-08 | — | — | US | disclosed |
| WO-2001072728-A2 | NOVEL PIPERAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| EP-0106123-B1 | NOVEL N-NITROSO COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND PROCESSES FOR THEIR PREPARATION | AB LEO (SE) | 1986-01-02 | — | — | EP | disclosed |
| EP-0106123-A1 | Novel N-nitroso compounds, compositions containing such compounds and processes for their preparation | AB LEO (SE) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058932-A1 | Novel piperazine derivatives | IL5, IL17A, CCR2 | GLS 1374/4885CASP3 800/4885CA9 4379/4885 |
| US-20150210672-A1 | ORGANIC COMPOUNDS | SLCO2B1, SLCO1B1, SLCO1B3 | GLS 2585/4885CASP3 1365/4885CA9 169/4885 |
| US-20160116840-A1 | COMPOUND, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, RESIST FILM USING SAME, RESIST-COATED MASK BLANK, PHOTOMASK, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | CHRM1, ESR1, RER1 | GLS 4821/4885CASP3 4276/4885CA9 4011/4885 |
| US-20070093665-A1 | Process for production of delta-9- tetrahydrocannabinol | CNR2, CNR1, HRH4 | GLS 4406/4885CASP3 3049/4885CA9 147/4885 |
| US-20020107255-A1 | Novel piperazine derivatives | IL5, IL17A, CCR2 | GLS 1374/4885CASP3 800/4885CA9 4379/4885 |
| US-20160185724-A1 | HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | HPD, HPGDS, EPX | GLS 266/4885CASP3 1202/4885CA9 2988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.