SCHEMBL14025834

SCHEMBL14025834

CCCc1ccc(S(=O)(=O)NC(CO)C(=O)NO)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 3/20 0.52
MMP2 P08253 2/20 0.52
MMP1 P03956 1/20 0.47
MMP14 P50281 1/20 0.47
ADAM17 P78536 1/20 0.47
MMP7 P09237 2/20 0.47
MMP10 P09238 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
F2 P00734 4/20 0.47
ALDH1A1 P00352 3/20 0.45
MMP13 P45452 2/20 0.44
LMNA P02545 2/20 0.44
FFAR4 Q5NUL3 1/20 0.44
F2R P25116 1/20 0.43
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4925180 1.00 MMP9 (0.52) MMP9MMP2MMP1MMP14ADAM17
SCHEMBL4921267 0.88 MMP9 (0.51) MMP9MMP2MMP1MMP14ADAM17
SCHEMBL4921260 0.88 MMP9 (0.51) MMP9MMP2MMP1MMP14ADAM17
SCHEMBL14045834 0.82 F2 (0.47) NPSR1F2ALDH1A1LMNAFFAR4
SCHEMBL14025835 0.80 MMP1 (0.58) MMP9MMP2MMP1MMP14ADAM17
SCHEMBL4926953 0.80 MMP1 (0.58) MMP9MMP2MMP1MMP14ADAM17
SCHEMBL5226437 0.80 MMP13 (0.58) MMP9MMP2MMP1MMP7MMP13
SCHEMBL1565606 0.80 MMP13 (0.58) MMP9MMP2MMP1MMP7MMP13
SCHEMBL1443795 0.79 MMP9 (0.54) MMP9MMP2MMP1MMP14ADAM17
SCHEMBL1443796 0.79 MMP9 (0.54) MMP9MMP2MMP1MMP14ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US disclosed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 MMP9 856/4885MMP2 428/4885MMP1 387/4885
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 MMP9 1037/4885MMP2 650/4885MMP1 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.