Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.58 |
| ▸ | MMP1 | P03956 | 5/20 | 0.58 |
| ▸ | MMP2 | P08253 | 5/20 | 0.58 |
| ▸ | MMP8 | P22894 | 3/20 | 0.58 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | BMP1 | P13497 | 8/20 | 0.55 |
| ▸ | MMP3 | P08254 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 2/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1565606 | 1.00 | MMP13 (0.58) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL7416701 | 0.89 | ALDH1A1 (0.58) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL7461414 | 0.88 | MMP13 (0.56) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL7417246 | 0.86 | MMP7 (0.65) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL5639380 | 0.86 | MMP2 (0.57) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL4621504 | 0.86 | MMP2 (0.66) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL4620929 | 0.86 | MMP2 (0.66) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL4619626 | 0.86 | MMP2 (0.66) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL8023829 | 0.84 | BMP1 (0.59) | MMP13MMP1MMP2MMP8MMP9 | |
| SCHEMBL8436170 | 0.83 | MMP13 (0.51) | MMP13MMP1MMP2MMP8MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781601-A2 | DERIVATIVES OF ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID AS MATRIX METALLOPROTEINASES INHIBITORS | Abiogen Pharma S.p.A. (IT) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006013193-A2 | DERIVATIVES OF ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID AS MATRIX METALLOPROTEINASES INHIBITORS | ABIOGEN PHARMA S.P.A. (IT) | 2006-02-09 | — | — | WO | disclosed |