Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028554 | 0.81 | TAS1R3 (0.41) | HCAR3ALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL11301102 | 0.81 | RAD52 (0.43) | HCAR3ALDH1A1KDM4EMAPTRAD52 | |
| SCHEMBL10412215 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4ECYP1A2MAPTCYP2C9 | |
| SCHEMBL4862775 | 0.80 | SIGMAR1 (0.43) | ALDH1A1KDM4ECYP1A2MAPTCYP2C9 | |
| SCHEMBL8372450 | 0.79 | SIGMAR1 (0.42) | ALDH1A1KDM4ECYP1A2MAPTCYP2C9 | |
| SCHEMBL8370672 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4ECYP1A2MAPTCYP2C9 | |
| SCHEMBL13626615 | 0.76 | KDM4E (0.48) | HCAR3ALDH1A1KDM4EMAPTCYP2D6 | |
| SCHEMBL6255738 | 0.75 | MAPT (0.49) | HCAR3ALDH1A1KDM4ECYP1A2MAPT | |
| SCHEMBL4951647 | 0.74 | ALDH1A1 (0.47) | HCAR3ALDH1A1KDM4EMAPTCYP2D6 | |
| SCHEMBL33659 | 0.74 | MAPT (0.46) | ALDH1A1KDM4ECYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |