Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860836 | 0.81 | FYN (0.44) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL14028541 | 0.81 | HCAR3 (0.42) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL13626620 | 0.78 | TAS1R3 (0.41) | TAS1R3TAS1R1TAS1R2MAPTALDH1A1 | |
| SCHEMBL3859936 | 0.76 | SIGMAR1 (0.44) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL4953753 | 0.76 | TDP1 (0.39) | TAS1R3TAS1R1TAS1R2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3859541 | 0.74 | MAPT (0.43) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4949145 | 0.74 | TDP1 (0.38) | TAS1R3TAS1R1TAS1R2MAPTALDH1A1 | |
| SCHEMBL9297193 | 0.73 | TAS1R3 (0.41) | TAS1R3TAS1R1TAS1R2ALDH1A1CRHR1 | |
| SCHEMBL4860025 | 0.73 | TLR7 (0.40) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL4956493 | 0.72 | MAPT (0.49) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |