Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077369 | 0.87 | CDK1 (0.42) | CDK1 | |
| SCHEMBL6292406 | 0.85 | L3MBTL1 (0.44) | CDK1 | |
| SCHEMBL27926712 | 0.81 | CDK1 (0.47) | CDK1SIGMAR1 | |
| SCHEMBL14030635 | 0.80 | ADRB2 (0.50) | CDK1SIGMAR1 | |
| SCHEMBL5050747 | 0.77 | SIGMAR1 (0.48) | SIGMAR1THRATHRB | |
| SCHEMBL4637738 | 0.76 | ADRB2 (0.41) | CDK1 | |
| SCHEMBL10076826 | 0.72 | MAOB (0.43) | — | |
| SCHEMBL10477860 | 0.72 | KDM4E (0.41) | — | |
| SCHEMBL19422886 | 0.71 | ADRB2 (0.48) | CDK1 | |
| SCHEMBL1411756 | 0.71 | ADRB2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648214-B2 | Processes suitable for the preparation of salmeterol | GENERICS [UK] LIMITED (GB) | 2014-02-11 | — | — | US | disclosed |
| US-20080262267-A1 | NOVEL PROCESS | GENERICS [UK] LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262267-A1 | NOVEL PROCESS | CYP4A11, HSD3B1, HSD11B1 | CDK1 2767/4885LTA4H 191/4885SIGMAR1 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.