Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | NPC1 | O15118 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | MAOA | P21397 | 1/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15802556 | 0.90 | CYP1A2 (0.68) | CYP1A2KDM4ELMNANPC1TP53 | |
| SCHEMBL3692541 | 0.88 | CYP1A2 (0.68) | CYP1A2KDM4ELMNANPC1TP53 | |
| Nabumetone SCHEMBL2256 | 0.87 | CYP1A2 (1.00) | CYP1A2KDM4ELMNANPC1TP53 | |
| SCHEMBL27706724 | 0.87 | CYP1A2 (0.77) | CYP1A2KDM4ELMNANPC1TP53 | |
| Nabumetone SCHEMBL29570823 | 0.87 | CYP1A2 (1.00) | CYP1A2KDM4ELMNANPC1TP53 | |
| Nabumetone SCHEMBL3853067 | 0.87 | CYP1A2 (1.00) | CYP1A2KDM4ELMNANPC1TP53 | |
| Nabumetone SCHEMBL29373228 | 0.87 | CYP1A2 (1.00) | CYP1A2KDM4ELMNANPC1TP53 | |
| SCHEMBL9670503 | 0.86 | CYP1A2 (0.67) | CYP1A2KDM4ELMNANPC1TP53 | |
| SCHEMBL4712374 | 0.85 | CYP1A2 (0.74) | CYP1A2KDM4ELMNANPC1TP53 | |
| Nabumetone SCHEMBL104942 | 0.85 | CYP1A2 (0.97) | CYP1A2KDM4ELMNANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071181-B2 | Metal nanoparticle and use thereof for inducing chirality in liquid crystal phases | UNIVERSITY OF MANITOBA (CA) | 2011-12-06 | — | — | US | claimed |
| US-20090027611-A1 | Metal Nanoparticle and Use Thereof for Inducing Chirality in Liquid Crystal Phases | THE UNIVERSITY OF MANITOBA (CA) | 2009-01-29 | — | — | US | claimed |
| US-20020183520-A1 | Process to prepare (5R)-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]-quinolin-2(1H)-one | WUTS PETER GUILLAUME MARIE (US) | 2002-12-05 | — | — | US | claimed |
| US-6355802-B1 | Process to prepare (5R)-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]-quinolin-2(1h)-one | PHARMACIA & UPJOHN COMPANY | 2002-03-12 | — | — | US | claimed |
| EP-1149100-A1 | PROCESS TO PREPARE (5R)-(METHYLAMINO)-5,6-DIHYDRO-4H-IMIDAZO 4,5,1-ij]-QUINOLIN-2(1H)-ONE | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-31 | — | — | EP | claimed |
| WO-2000046226-A1 | PROCESS TO PREPARE (5R)-(METHYLAMINO)-5,6-DIHYDRO-4H-IMIDAZO[4,5,1-ij]-QUINOLIN-2(1H)-ONE | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-10 | — | — | WO | claimed |
| US-4857462-A | Process for obtaining D(+)-naproxen | BOEHRINGER MANNHEIM GMBH (DE) | 1989-08-15 | — | — | US | claimed |
| US-4723033-A | REACTING ALPHA METAL ACID DERIVATIVE AND ARYL HALIDE WITH OPTICALLY ACTIVE CATALYST | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1988-02-02 | — | — | US | claimed |
| WO-2023171757-A1 | POLYMER COMPOSITION, SINGLE LAYER PHASE DIFFERENCE MATERIAL, AND LIQUID CRYSTAL ALIGNMENT AGENT | 日産化学株式会社 | 2023-09-14 | — | — | WO | disclosed |
| US-10788713-B2 | Patterned liquid crystal alignment using ink-jet printed nanoparticles and use thereof to produce patterned, electro-optically addressable devices; ink-jet printable compositions | KENT STATE UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-10545383-B2 | Patterned liquid crystal alignment using ink-jet printed nanoparticles and use thereof to produce patterned, electro-optically addressable devices; ink-jet printable compositions | KENT STATE UNIVERSITY (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190084943-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY | PARION SCIENCES, INC. (US) | 2019-03-21 | — | — | US | disclosed |
| US-20190085245-A1 | Patterned Liquid Crystal Alignment Using Ink-Jet Printed Nanoparticles and Use Thereof to Produce Patterned, Electro-Optically Addressable Devices; Ink-Jet Printable Compositions | KENT STATE UNIVERSITY | 2019-03-21 | — | — | US | disclosed |
| US-20190085244-A1 | Patterned Liquid Crystal Alignment Using Ink-Jet Printed Nanoparticles and Use Thereof to Produce Patterned, Electro-Optically Addressable Devices; Ink-Jet Printable Compositions | KENT STATE UNIVERSITY (US) | 2019-03-21 | — | — | US | disclosed |
| US-4605758-A | Preparation of α-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1986-08-12 | — | — | US | disclosed |
| EP-0178580-A2 | Intermediates for the synthesis of carboxylic acids | ZAMBON S.p.A. (IT) | 1986-04-23 | — | — | EP | disclosed |
| EP-0163338-A1 | Process for preparing naproxen | Nobel Chemicals AB (SE) | 1985-12-04 | — | — | EP | disclosed |
| EP-0022529-B1 | PROCESS FOR THE RESOLUTION OF D,L 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID; A MIXTURE OF THE SALTS OF THESE D AND L ACIDS; A PHARMACEUTICAL COMPOSITION CONTAINING A SALT OF THE D ACID; A SALT OF THE D ACID | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-06-29 | — | — | EP | disclosed |
| EP-0081993-A2 | Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-06-22 | — | — | EP | disclosed |
| US-3936528-A | 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR SALT AND CODEINE OR PROPOXYPHENE | SYNTEX CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090027611-A1 | Metal Nanoparticle and Use Thereof for Inducing Chirality in Liquid Crystal Phases | NCL, AUP1, PIN1 | CYP1A2 3130/4885KDM4E 3963/4885LMNA 3358/4885 |
| US-20020183520-A1 | Process to prepare (5R)-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]-quinolin-2(1H)-one | CYP2S1, HTR3C, HTR3A | CYP1A2 21/4885KDM4E 304/4885LMNA 400/4885 |
| US-20190084943-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY | SCNN1B, SCNN1A, SCNN1G | CYP1A2 1710/4885KDM4E 2881/4885LMNA 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.