SCHEMBL14035918

SCHEMBL14035918

O=C(OCCOc1cccc2ccccc12)C(F)(F)OOS

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTR1B P28222 6/20 0.44
KCNA3 P22001 1/20 0.43
MCL1 Q07820 6/20 0.42
BCL2 P10415 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAD Q92934 2/20 0.42
ALB P02768 1/20 0.42
HTR1D P28221 2/20 0.42
OGG1 O15527 1/20 0.42
ATM Q13315 1/20 0.41
SLC6A4 P31645 1/20 0.41
HRH1 P35367 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14035720 0.86 IDO1 (0.40) KDM4EALDH1A1HPGD
SCHEMBL14035915 0.84 TRPV1 (0.42) KDM4EALDH1A1TDP1MCL1
SCHEMBL12128704 0.82 KDM4E (0.53) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL14035684 0.81 HSD17B10 (0.48) KDM4EALDH1A1HPGDTDP1OGG1
SCHEMBL13842647 0.79 KDM4E (0.45) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL2605920 0.79 KDM4E (0.47) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL14035923 0.79 PPARG (0.48) KDM4EALDH1A1HPGDTDP1MCL1
SCHEMBL14035904 0.78 EPHX1 (0.44) HPGDTDP1ATM
SCHEMBL14009409 0.78 ALDH1A1 (0.46) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL13842639 0.77 MCL1 (0.45) KDM4EALDH1A1HPGDTDP1HTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274426-A1 Using acrylic ester and sulfonium said salt; high resolution semiconductors; microfabrication patterns; excimer laser lithography SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US disclosed