SCHEMBL140371

SCHEMBL140371

CCc1ccc[c]c1CCCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 2/20 0.40
SLC6A3 Q01959 2/20 0.40
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40
KCNH2 Q12809 1/20 0.40
HTR2A P28223 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
HDAC3 O15379 1/20 0.38
MAPK1 P28482 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5150284 0.90 HTT (0.41) HTR1AKCNH2KMT2AMEN1TP53
SCHEMBL6570928 0.88 HTR2A (0.42) ADRA1ASLC6A3HTR2AHDAC3MAPK1
SCHEMBL5332631 0.87 KCNH2 (0.40) ADRA1ASLC6A3CHRM2HTR1AADRA2A
SCHEMBL6468704 0.83 KCNH2 (0.45) KCNH2HTR2AL3MBTL1
SCHEMBL10894648 0.83 KCNH2 (0.49) SLC6A3CHRM2ADRA2ACHRM1SLC6A2
SCHEMBL815623 0.82 GABRA1 (0.34) HTR1ADRD3KCNH2HTR2ACYP2D6
SCHEMBL815924 0.81 LIPG (0.41) KCNH2
SCHEMBL983400 0.79 LIPG (0.43) KCNH2
SCHEMBL815247 0.79 LIPG (0.43) KCNH2
SCHEMBL982662 0.79 LIPG (0.43) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948182-B1 METHOD FOR TREATING NEURONAL AND NON-NEURONAL PAIN ZHUO MIN (CA) 2012-12-12 EP claimed
US-20240034825-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC POLYMERIZATION OF CONJUGATED DIENES AND LIQUID POLYMERS THEREOF ALBEMARLE CORPORATION 2024-02-01 US disclosed
WO-2023168218-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-09-07 WO disclosed
EP-4208485-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC POLYMERIZATION OF CONJUGATED DIENES AND LIQUID POLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-07-12 EP disclosed
CN-116368159-A Process and catalyst for hydrogen-mediated anionic polymerization of conjugated dienes and liquid polymers thereof 雅宝公司 2023-06-30 CN disclosed
EP-2683749-B1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS GRACE W R & CO (US) 2023-06-07 EP disclosed
EP-2991995-A1 BUTADIEN2,3-DIYL LINKED DI-DOPO DERIVATIVES AS FLAME RETARDANTS Albemarle Corporation (US) 2016-03-09 EP disclosed
US-20160060281-A1 BUTADIEN2,3-DIYL LINKED DI-DOPO DERIVATIVES AS FLAME RETARDANTS ANGELL SCOTT EDWARD (US) 2016-03-03 US disclosed
US-9090720-B2 Aluminoxane catalyst activators containing carbocation agents, and use thereof in polyolefin catalysts ALBEMARLE CORPORATION (US) 2015-07-28 US disclosed
WO-2015103006-A1 FLAME RETARDANT THERMOPLASTIC COMPOSITIONS ALBEMARLE CORPORATION (US) 2015-07-09 WO disclosed
EP-2432790-B1 DOPO-DERIVED FLAME RETARDANT AND EPOXY RESIN COMPOSITION ALBEMARLE CORP (US) 2015-07-08 EP disclosed
WO-2014179688-A1 BUTADIEN2,3-DIYL LINKED DI-DOPO DERIVATIVES AS FLAME RETARDANTS ALBEMARLE CORPORATION (US) 2014-11-06 WO disclosed
EP-2683749-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS Albemarle Corporation (US) 2014-01-15 EP disclosed
US-20130345376-A1 Aluminoxane Catalyst Activators Containing Carbocation Agents, and use thereof in Polyolefin Catalysts ALBEMARLE CORPORATION (US) 2013-12-26 US disclosed
US-8536256-B2 DOPO-derived flame retardant and epoxy resin composition ALBEMARLE CORPORATION (US) 2013-09-17 US disclosed
WO-2012122332-A1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS ALBEMARLE CORPORATION (US) 2012-09-13 WO disclosed
WO-2012064703-A1 DOPO-DERIVED FLAME RETARDANT AND SYNTHETIC HYDROGARNETS FOR EPOXY RESIN COMPOSITIONS ALBEMARLE CORPORATION (US) 2012-05-18 WO disclosed
EP-2432790-A1 DOPO-DERIVED FLAME RETARDANT AND EPOXY RESIN COMPOSITION Albemarle Corporation (US) 2012-03-28 EP disclosed
US-20120055705-A1 DOPO-DERIVED FLAME RETARDANT AND EPOXY RESIN COMPOSITION ALBEMARLE CORPORATION (US) 2012-03-08 US disclosed
WO-2010135393-A1 DOPO-DERIVED FLAME RETARDANT AND EPOXY RESIN COMPOSITION ALBEMARLE CORPORATION (US) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120055705-A1 DOPO-DERIVED FLAME RETARDANT AND EPOXY RESIN COMPOSITION FLAD1, P2RY10, P2RY11 ADRA1A 940/4885SLC6A3 2266/4885CHRM2 3934/4885
US-20160060281-A1 BUTADIEN2,3-DIYL LINKED DI-DOPO DERIVATIVES AS FLAME RETARDANTS DUOX2, FFAR2, BBOX1 ADRA1A 909/4885SLC6A3 1623/4885CHRM2 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.