Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040609 | 0.75 | ALDH1A1 (0.38) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL11040612 | 0.75 | ALDH1A1 (0.38) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL8884914 | 0.73 | ALDH1A1 (0.40) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL5983334 | 0.70 | PKM (0.35) | ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL14015886 | 0.66 | TP53 (0.34) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL14015875 | 0.65 | L3MBTL1 (0.38) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL7537535 | 0.63 | ALDH1A1 (0.43) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL19533902 | 0.63 | ALDH1A1 (0.43) | ALDH1A1CHRM2OPRM1DDB1CRBN | |
| SCHEMBL11043276 | 0.60 | CA9 (0.40) | ALDH1A1CHRM2TSHRRAB9AHSD17B10 | |
| SCHEMBL11043274 | 0.60 | CA9 (0.40) | ALDH1A1CHRM2TSHRRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262224-A1 | Method of Preparation of Benzofuran-2-Carboxylic Acid -Amide | SMITHKLINE BEECHAM CORPORATION | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262224-A1 | Method of Preparation of Benzofuran-2-Carboxylic Acid -Amide | ACMSD, CPS1, BCAT2 | ALDH1A1 104/4885CHRM2 2718/4885OPRM1 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.