Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930709 | 0.81 | MMP1 (0.68) | MMP1ADAMTS4MMP2MMP13MMP14 | |
| SCHEMBL14052271 | 0.76 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EGAAOPRK1 | |
| SCHEMBL23343636 | 0.75 | CA12 (0.60) | ALDH1A1SMN1; SMN2KDM4EGAAOPRK1 | |
| SCHEMBL14045835 | 0.74 | ALDH1A1 (0.44) | ALDH1A1OPRK1CA2MMP2MMP13 | |
| SCHEMBL14045734 | 0.74 | SLC1A2 (0.46) | ALDH1A1MMP1OPRK1ADAMTS4MMP2 | |
| SCHEMBL23052429 | 0.71 | LMNA (0.51) | ALDH1A1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL14616696 | 0.71 | NPC1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL14280991 | 0.71 | MMP1 (0.62) | ALDH1A1SMN1; SMN2KDM4ENPC1GAA | |
| SCHEMBL23052525 | 0.70 | CA12 (0.63) | ALDH1A1SMN1; SMN2KDM4EOPRK1CA12 | |
| SCHEMBL5090951 | 0.70 | CA1 (0.57) | ALDH1A1SMN1; SMN2KDM4ENPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | ALDH1A1 28/4885SMN1; SMN2 1214/4885KDM4E 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.