SCHEMBL14045835

SCHEMBL14045835

CCC(C)(C)c1ccc(S(=O)(=O)NC(CO)C(=O)ON)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
SLC1A2 P43004 2/20 0.41
F2 P00734 1/20 0.40
F10 P00742 1/20 0.40
PLG P00747 1/20 0.40
PLAU P00749 1/20 0.40
ST14 Q9Y5Y6 1/20 0.40
MMP9 P14780 4/20 0.39
MMP7 P09237 2/20 0.39
MMP10 P09238 1/20 0.39
CASP1 P29466 1/20 0.38
MMP2 P08253 3/20 0.37
EEF2K O00418 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
OPRK1 P41145 1/20 0.37
MMP3 P08254 1/20 0.36
MMP13 P45452 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A1 P43005 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14045734 0.83 SLC1A2 (0.46) ALDH1A1MAPTSLC1A2MMP9MMP7
SCHEMBL1443796 0.82 MMP9 (0.54) ALDH1A1MAPTMMP9MMP7MMP10
SCHEMBL1443795 0.82 MMP9 (0.54) ALDH1A1MAPTMMP9MMP7MMP10
SCHEMBL14045834 0.80 F2 (0.47) ALDH1A1F2L3MBTL1CA2
SCHEMBL14539390 0.79 MMP2 (0.42) ALDH1A1MAPTMMP9MMP2L3MBTL1
SCHEMBL14045785 0.78 MMP2 (0.57) SLC1A2MMP9MMP7MMP2MMP3
SCHEMBL5182133 0.77 MMP9 (0.53) ALDH1A1MAPTSLC1A2MMP9MMP7
SCHEMBL5180159 0.75 MMP9 (0.54) ALDH1A1MAPTMMP9MMP7MMP10
SCHEMBL14045869 0.74 ALDH1A1 (0.49) ALDH1A1CASP1MMP2OPRK1MMP13
SCHEMBL14045891 0.72 SLC1A3 (0.53) ALDH1A1SLC1A2F2F10PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 ALDH1A1 28/4885MAPT 294/4885SLC1A2 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.