Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046898 | 0.91 | DGAT1 (0.47) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL14046889 | 0.89 | THRB (0.50) | NPBWR1MAPTHPGDALDH1A1HTT | |
| SCHEMBL3098570 | 0.87 | MMP2 (0.57) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL11948998 | 0.87 | HDAC6 (0.48) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL14046893 | 0.86 | HPGD (0.46) | MMP2MMP9MMP8MMP13NPBWR1 | |
| SCHEMBL14046894 | 0.86 | MAPT (0.45) | NPBWR1MAPTMAPK1HPGDALDH1A1 | |
| SCHEMBL11949012 | 0.86 | MMP2 (0.64) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL14046899 | 0.84 | KMT2A (0.51) | NPBWR1MAPTHPGDALDH1A1HTT | |
| SCHEMBL3104076 | 0.84 | MMP2 (0.59) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL11956752 | 0.84 | MMP2 (0.56) | MMP2MMP9MMP8MMP13HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130669-A1 | BENZIMIDAZOLES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-10-30 | — | — | WO | disclosed |