Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046889 | 0.89 | THRB (0.50) | MAPTSMN1; SMN2TP53NPBWR1ALDH1A1 | |
| SCHEMBL11949064 | 0.87 | ABL1 (0.45) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL14046895 | 0.86 | MMP2 (0.48) | MAPTSMN1; SMN2NPBWR1ALDH1A1HPGD | |
| SCHEMBL14046898 | 0.85 | DGAT1 (0.47) | MAPTSMN1; SMN2TP53NPBWR1ALDH1A1 | |
| SCHEMBL14046899 | 0.84 | KMT2A (0.51) | MAPTSMN1; SMN2NPBWR1ALDH1A1HPGD | |
| SCHEMBL14046893 | 0.84 | HPGD (0.46) | MAPTSMN1; SMN2NPBWR1ALDH1A1HPGD | |
| SCHEMBL14046891 | 0.82 | RAB9A (0.48) | MAPTSMN1; SMN2TP53NPBWR1ALDH1A1 | |
| SCHEMBL14046892 | 0.82 | TUBB4A (0.42) | MAPTSMN1; SMN2NPBWR1ALDH1A1HPGD | |
| SCHEMBL14046897 | 0.81 | TUBB4A (0.45) | MAPTSMN1; SMN2NPBWR1ALDH1A1HPGD | |
| SCHEMBL11949050 | 0.79 | ABL1 (0.44) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130669-A1 | BENZIMIDAZOLES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-10-30 | — | — | WO | disclosed |