Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949053 | 0.88 | KMT2A (0.45) | CDK2ALDH1A1KDRABL1 | |
| SCHEMBL14046889 | 0.87 | THRB (0.50) | HPGDRAB9AHTTSMN1; SMN2NPBWR1 | |
| SCHEMBL14046895 | 0.86 | MMP2 (0.48) | HPGDRAB9AHTTSMN1; SMN2NPBWR1 | |
| SCHEMBL14046894 | 0.84 | MAPT (0.45) | HPGDRAB9AHTTSMN1; SMN2NPBWR1 | |
| SCHEMBL14046899 | 0.82 | KMT2A (0.51) | HPGDRAB9AHTTSMN1; SMN2NPBWR1 | |
| SCHEMBL11949063 | 0.82 | KDR (0.50) | HPGDRAB9AHTTSMN1; SMN2PARP14 | |
| SCHEMBL14046892 | 0.80 | TUBB4A (0.42) | HPGDRAB9AHTTSMN1; SMN2NPBWR1 | |
| SCHEMBL14046891 | 0.80 | RAB9A (0.48) | HPGDRAB9AHTTSMN1; SMN2NPBWR1 | |
| SCHEMBL14046898 | 0.80 | DGAT1 (0.47) | HPGDSMN1; SMN2NPBWR1KITALDH1A1 | |
| SCHEMBL14046897 | 0.79 | TUBB4A (0.45) | HPGDRAB9AHTTSMN1; SMN2NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130669-A1 | BENZIMIDAZOLES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-10-30 | — | — | WO | disclosed |