Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046891 | 0.95 | RAB9A (0.48) | KMT2AGBA1NPBWR1NPC1RAB9A | |
| SCHEMBL11949067 | 0.88 | KMT2A (0.47) | KMT2AHTTNPSR1ABL1SMN1; SMN2 | |
| SCHEMBL14046889 | 0.87 | THRB (0.50) | KMT2ANPBWR1NPC1RAB9ABRD4 | |
| SCHEMBL15275517 | 0.84 | SMN1; SMN2 (0.46) | KMT2ANPC1RAB9AHTTNPSR1 | |
| SCHEMBL11948986 | 0.84 | SMN1; SMN2 (0.48) | KMT2ANPC1RAB9AHTTNPSR1 | |
| SCHEMBL14046895 | 0.84 | MMP2 (0.48) | NPBWR1NPC1RAB9AHTTNPSR1 | |
| SCHEMBL14046894 | 0.84 | MAPT (0.45) | KMT2ANPBWR1NPC1RAB9AHTT | |
| SCHEMBL11949060 | 0.83 | SMN1; SMN2 (0.50) | KMT2ANPC1RAB9AHTTNPSR1 | |
| SCHEMBL3092628 | 0.83 | KDM4E (0.52) | KMT2ANPC1RAB9AHTTNPSR1 | |
| SCHEMBL14046893 | 0.82 | HPGD (0.46) | NPBWR1NPC1RAB9AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130669-A1 | BENZIMIDAZOLES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-10-30 | — | — | WO | disclosed |