Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12965355 | 0.87 | TRPA1 (0.38) | ESR1ESR2MAPK1 | |
| SCHEMBL825660 | 0.84 | ESR1 (0.44) | ESR1ESR2APPMIFPDCD1 | |
| SCHEMBL14066976 | 0.84 | NQO2 (0.35) | ESR1ESR2APPMIFADRB1 | |
| SCHEMBL20090404 | 0.81 | ESR1 (0.47) | ESR1ESR2MIFPDCD1CD274 | |
| SCHEMBL8850119 | 0.78 | APP (0.49) | ESR1ESR2APPMIFPDCD1 | |
| SCHEMBL14067018 | 0.78 | ELANE (0.53) | ESR1ESR2MIF | |
| SCHEMBL15697338 | 0.78 | ESR1 (0.47) | ESR1ESR2MIF | |
| SCHEMBL8628683 | 0.78 | ESR1 (0.47) | ESR1ESR2MIF | |
| SCHEMBL19679939 | 0.77 | ESR1 (0.37) | ESR1ESR2APPMIFADRB2 | |
| SCHEMBL1617663 | 0.77 | LMNA (0.43) | ESR1ESR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501382-B1 | Acid amplifiers | THE RESEARCH FOUNDATION OF STATE UNIV. OF NEW YORK (US) | 2013-08-06 | — | — | US | disclosed |
| US-8501382-B1 | Acid amplifiers | THE RESEARCH FOUNDATION OF STATE UNIV. OF NEW YORK (US) | 2013-08-06 | — | — | US | disclosed |
| US-20080220597-A1 | Photoresists and methods for use thereof | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-09-11 | — | — | US | disclosed |
| US-7297616-B2 | Methods, photoresists and substrates for ion-implant lithography | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2007-11-20 | — | — | US | disclosed |