Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025560 | 0.88 | ALDH1A1 (0.53) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL14068058 | 0.88 | NAMPT (0.48) | ALDH1A1HTTMAPK1LMNANPC1 | |
| SCHEMBL15676806 | 0.78 | ALDH1A1 (0.57) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL14025570 | 0.78 | CASP3 (0.49) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL14025574 | 0.77 | TAAR1 (0.44) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL14025548 | 0.76 | PKM (0.53) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL14025567 | 0.75 | HTT (0.53) | POLBALDH1A1HTTKDM4ELMNA | |
| SCHEMBL14068310 | 0.75 | DRD2 (0.55) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL14025576 | 0.75 | ITGB3 (0.51) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL14025577 | 0.75 | HTT (0.50) | MEN1KMT2AALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |