Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738064 | 0.80 | AVPR1A (0.34) | AVPR1ASPRLMNATSHRNPSR1 | |
| SCHEMBL4574346 | 0.77 | HTT (0.34) | AVPR1AOXTRSPRHTTPDK2 | |
| SCHEMBL4783797 | 0.76 | RORC (0.38) | AVPR1AHTTLMNATSHR | |
| SCHEMBL4596912 | 0.75 | LMNA (0.35) | AVPR1ASPRHTTLMNATSHR | |
| SCHEMBL4595427 | 0.74 | LMNA (0.35) | AVPR1ASPRHTTLMNATSHR | |
| SCHEMBL14068681 | 0.73 | DHODH (0.36) | ACACBDHODH | |
| SCHEMBL4735036 | 0.72 | CNR1 (0.36) | HRH4LMNA | |
| SCHEMBL4740444 | 0.70 | HCAR2 (0.34) | DHODH | |
| SCHEMBL4734328 | 0.69 | CCNC (0.32) | — | |
| SCHEMBL4735029 | 0.68 | NPY5R (0.33) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114123-A1 | SPIRO BENZIMIDAZOLE DERIVATIVES AS ACID PUMP INHIBITORS | RAQUALIA PHARMA INC. (JP) | 2008-09-25 | — | — | WO | disclosed |