Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 5/20 | 0.47 |
| ▸ | FLT4 | P35916 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028416 | 0.80 | CA2 (0.55) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL1406895 | 0.79 | FLT1 (0.47) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL14543865 | 0.77 | F2 (0.50) | LMNATMPRSS6 | |
| SCHEMBL14300761 | 0.76 | LMNA (0.47) | LMNATMPRSS6CA1CA2CA9 | |
| SCHEMBL15258016 | 0.74 | HPGD (0.47) | MEN1LMNAKMT2ACA1CA9 | |
| Sulfaguanidine SCHEMBL4347029 | 0.73 | TSHR (0.61) | MEN1LMNAKMT2ACA1CA2 | |
| Sulfaguanidine SCHEMBL93639 | 0.73 | TSHR (0.61) | MEN1LMNAKMT2ACA1CA2 | |
| SCHEMBL2933980 | 0.72 | MMP2 (0.57) | FLT1FLT4KDRCA1CA2 | |
| Sulfaguanidine SCHEMBL28848861 | 0.72 | TSHR (0.59) | MEN1LMNAKMT2ACA1CA2 | |
| Sulfaguanidine SCHEMBL28627621 | 0.72 | TSHR (0.59) | MEN1LMNAKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295053-B1 | Novel 2H-chromen-2-one-3-carboxamides for medical uses | INST MATERIA MEDICA CAMS (CN) | 2016-10-19 | — | — | EP | claimed |
| EP-2295053-A1 | Novel 2H-chromen-2-one-3-carboxamides for medical uses | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2011-03-16 | — | — | EP | claimed |
| US-20060148834-A1 | Novel coumarin-amide derivatives and its preparation, said drug composition and its use | INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2006-07-06 | — | — | US | claimed |
| EP-1570846-A1 | THE NOVEL COUMARIN-AMIDE DERIVATIVES AND ITS PREPARATION, SAID DRUG COMPOSITION AND ITS USE | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2005-09-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148834-A1 | Novel coumarin-amide derivatives and its preparation, said drug composition and its use | INSR, GLS, INSRR | FLT1 76/4885FLT4 86/4885KDR 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.