Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14073522 | 0.91 | KMT2A (0.60) | CYP3A4CYP19A1CYP2C9MAPK14ALDH1A1 | |
| SCHEMBL30444601 | 0.83 | KMT2A (0.62) | CYP3A4CYP19A1CYP2C9MAPK14ALDH1A1 | |
| SCHEMBL14073692 | 0.82 | ALDH1A1 (0.72) | CYP3A4CYP19A1CYP2C9ALDH1A1MAPT | |
| SCHEMBL14073778 | 0.81 | CYP3A4 (0.61) | CYP3A4CYP19A1CYP2C9ALDH1A1MAPT | |
| SCHEMBL14073742 | 0.81 | RAB9A (0.64) | CYP3A4CYP19A1CYP2C9ALDH1A1MAPT | |
| SCHEMBL14073845 | 0.80 | CYP3A4 (0.82) | CYP3A4CYP19A1CYP2C9ALDH1A1MAPT | |
| SCHEMBL14073031 | 0.80 | ALDH1A1 (0.69) | CYP3A4CYP19A1CYP2C9ALDH1A1MAPT | |
| SCHEMBL14073934 | 0.80 | ROCK2 (0.57) | CYP3A4CYP19A1CYP2C9ALDH1A1MAPT | |
| SCHEMBL14073735 | 0.79 | KMT2A (0.61) | CYP3A4CYP19A1CYP2C9ALDH1A1MAPT | |
| SCHEMBL24508699 | 0.79 | CYP3A4 (0.54) | CYP3A4CYP19A1CYP2C9MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | MMP12, MMP13, MMP25 | CYP3A4 376/4885CYP19A1 651/4885CYP2C9 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.