SCHEMBL1408588

SCHEMBL1408588

C=C(C)c1ccc(C(=C)C)c(C(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.38
RXRA P19793 3/20 0.37
GABRA1 P14867 3/20 0.33
HSP90AA1 P07900 3/20 0.33
HSP90AB1 P08238 3/20 0.33
GABRB1 P18505 2/20 0.33
SORT1 Q99523 1/20 0.32
LRRK2 Q5S007 1/20 0.32
LMNA P02545 2/20 0.31
SLC6A2 P23975 2/20 0.31
HTR2B P41595 2/20 0.31
TRPA1 O75762 1/20 0.31
CHRM1 P11229 1/20 0.31
ADRA1A P35348 1/20 0.31
RARB P10826 1/20 0.31
RARG P13631 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5143785 0.84 ACE2 (0.38) ACE2RXRAGABRA1GABRB1SORT1
SCHEMBL7912361 0.80 CA1 (0.37) GABRA1HSP90AA1HSP90AB1GABRB1LMNA
SCHEMBL7912415 0.80 HSP90AA1 (0.51) GABRA1HSP90AA1HSP90AB1GABRB1LMNA
SCHEMBL24006703 0.78 HRH4 (0.38) RXRALMNASLC6A2HTR2BTRPA1
SCHEMBL29434188 0.76 SORT1 (0.39) SORT1LMNA
SCHEMBL4511056 0.76 SORT1 (0.39) SORT1LMNA
SCHEMBL4776336 0.76 LMNA (0.53) ACE2GABRA1HSP90AA1HSP90AB1GABRB1
SCHEMBL20757271 0.74 TDP1 (0.37) ACE2LRRK2LMNASLC6A2HTR2B
SCHEMBL10595471 0.74 KAT6A (0.38) RXRAGABRA1GABRB1LMNASLC6A2
SCHEMBL30104503 0.74 SORT1 (0.38) RXRASORT1LMNASLC6A2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7226964-B2 Composition comprising a nitroxide, a promoter and optionally a free-radical initiator ARKEMA FRANCE (FR) 2007-06-05 US claimed
US-20040195550-A1 Composition comprising a nitroxide, a promoter and optionally a free-radical initiator ATOFINA 2004-10-07 US claimed
EP-1322696-B1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR ATOFINA (FR) 2004-08-25 EP claimed
EP-1322696-A1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR Atofina (FR) 2003-07-02 EP claimed
WO-2002028946-A1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR ATOFINA (FR) 2002-04-11 WO claimed
EP-0522729-B1 Composition for cross linking ethylene polymer, method for cross linking the polymer, and electric power cable providing the cross linked polymer NIPPON OILS & FATS CO LTD (JP) 1995-11-02 EP claimed
EP-0522729-A1 Composition for cross linking ethylene polymer, method for cross linking the polymer, and electric power cable providing the cross linked polymer NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-01-13 EP claimed
US-11753522-B2 Use of magnesium oxide for crosslinking polymers ARKEMA FRANCE (FR) 2023-09-12 US disclosed
US-20210002454-A1 USE OF MAGNESIUM OXIDE FOR CROSSLINKING POLYMERS ARKEMA FRANCE (FR) 2021-01-07 US disclosed
EP-3759163-A1 USE OF MAGNESIUM OXIDE FOR CROSSLINKING POLYMERS ARKEMA FRANCE (FR) 2021-01-06 EP disclosed
EP-3758956-A1 USE OF MAGNESIUM OXIDE IN TYRE MANUFACTURE ARKEMA FRANCE (FR) 2021-01-06 EP disclosed
WO-2020216635-A1 TYRE FOR A MANUALLY TRANSPORTABLE VEHICLE WHEEL COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-10-29 WO disclosed
CN-111770956-A Use of magnesium oxide for crosslinking polymers 阿科玛法国公司 2020-10-13 CN disclosed
EP-1322696-B1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR ATOFINA (FR) 2004-08-25 EP disclosed
EP-1322696-A1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR Atofina (FR) 2003-07-02 EP disclosed
WO-2002077089-A1 CROSSLINKING COMPOSITION AND CROSSLINKABLE COMPOSITION ATOFINA (FR) 2002-10-03 WO disclosed
WO-2002028946-A1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR ATOFINA (FR) 2002-04-11 WO disclosed
EP-0522729-B1 Composition for cross linking ethylene polymer, method for cross linking the polymer, and electric power cable providing the cross linked polymer NIPPON OILS & FATS CO LTD (JP) 1995-11-02 EP disclosed
US-5252676-A Diisopropenyl benzene and either dicumyl peroxide or bis (tert-butylperoxyisopropyl) benzene NIPPON OIL & FATS CO., LTD. (JP) 1993-10-12 US disclosed
EP-0522729-A1 Composition for cross linking ethylene polymer, method for cross linking the polymer, and electric power cable providing the cross linked polymer NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-01-13 EP disclosed