SCHEMBL5143785

SCHEMBL5143785

C=C(C)c1ccc(C(C)C)c(C(=C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 2/20 0.38
GABRA1 P14867 4/20 0.35
LMNA P02545 2/20 0.35
SLC6A2 P23975 2/20 0.35
HTR2B P41595 2/20 0.35
GABRB2 P47870 2/20 0.35
GABRB1 P18505 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
FAAH O00519 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
PTGS1 P23219 1/20 0.35
HTR2C P28335 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1408588 0.84 ACE2 (0.38) ACE2GABRA1LMNASLC6A2HTR2B
SCHEMBL4776336 0.80 LMNA (0.53) ACE2GABRA1LMNASLC6A2HTR2B
SCHEMBL20757271 0.78 TDP1 (0.37) ACE2LMNASLC6A2HTR2BCYP1A2
SCHEMBL4511056 0.76 SORT1 (0.39) LMNASORT1
SCHEMBL29434188 0.76 SORT1 (0.39) LMNASORT1
SCHEMBL7912415 0.76 HSP90AA1 (0.51) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL10891500 0.76 BCL2 (0.35) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL19417841 0.76 RAB9A (0.41) CA1CA2CYP1A2CYP3A4TSHR
SCHEMBL10595471 0.74 KAT6A (0.38) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL1362730 0.74 GABRA1 (0.50) GABRA1LMNASLC6A2HTR2BGABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7226964-B2 Composition comprising a nitroxide, a promoter and optionally a free-radical initiator ARKEMA FRANCE (FR) 2007-06-05 US claimed
US-20040195550-A1 Composition comprising a nitroxide, a promoter and optionally a free-radical initiator ATOFINA 2004-10-07 US claimed
EP-1322696-B1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR ATOFINA (FR) 2004-08-25 EP claimed
EP-1322696-A1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR Atofina (FR) 2003-07-02 EP claimed
WO-2002028946-A1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR ATOFINA (FR) 2002-04-11 WO claimed
EP-0522729-B1 Composition for cross linking ethylene polymer, method for cross linking the polymer, and electric power cable providing the cross linked polymer NIPPON OILS & FATS CO LTD (JP) 1995-11-02 EP claimed
EP-0522729-A1 Composition for cross linking ethylene polymer, method for cross linking the polymer, and electric power cable providing the cross linked polymer NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-01-13 EP claimed
US-11753522-B2 Use of magnesium oxide for crosslinking polymers ARKEMA FRANCE (FR) 2023-09-12 US disclosed
US-20210002454-A1 USE OF MAGNESIUM OXIDE FOR CROSSLINKING POLYMERS ARKEMA FRANCE (FR) 2021-01-07 US disclosed
EP-3759163-A1 USE OF MAGNESIUM OXIDE FOR CROSSLINKING POLYMERS ARKEMA FRANCE (FR) 2021-01-06 EP disclosed
EP-3758956-A1 USE OF MAGNESIUM OXIDE IN TYRE MANUFACTURE ARKEMA FRANCE (FR) 2021-01-06 EP disclosed
WO-2020216635-A1 TYRE FOR A MANUALLY TRANSPORTABLE VEHICLE WHEEL COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-10-29 WO disclosed
CN-111770956-A Use of magnesium oxide for crosslinking polymers 阿科玛法国公司 2020-10-13 CN disclosed
EP-1322696-B1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR ATOFINA (FR) 2004-08-25 EP disclosed
EP-1322696-A1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR Atofina (FR) 2003-07-02 EP disclosed
WO-2002077089-A1 CROSSLINKING COMPOSITION AND CROSSLINKABLE COMPOSITION ATOFINA (FR) 2002-10-03 WO disclosed
WO-2002028946-A1 COMPOSITION COMPRISING A NITROXIDE, A PROMOTER AND OPTIONALLY A FREE RADICAL INITIATOR ATOFINA (FR) 2002-04-11 WO disclosed
EP-0522729-B1 Composition for cross linking ethylene polymer, method for cross linking the polymer, and electric power cable providing the cross linked polymer NIPPON OILS & FATS CO LTD (JP) 1995-11-02 EP disclosed
US-5252676-A Diisopropenyl benzene and either dicumyl peroxide or bis (tert-butylperoxyisopropyl) benzene NIPPON OIL & FATS CO., LTD. (JP) 1993-10-12 US disclosed
EP-0522729-A1 Composition for cross linking ethylene polymer, method for cross linking the polymer, and electric power cable providing the cross linked polymer NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1993-01-13 EP disclosed