SCHEMBL140910

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5696465	0.86	LMNA (0.60)	KMT2AMASP2CFDMEN1PKM
	SCHEMBL27972037	0.86	KMT2A (0.54)	KMT2AMASP2CFDMEN1PKM
	SCHEMBL449366	0.84	L3MBTL1 (0.58)	KMT2AMASP2CFDMEN1PKM
	SCHEMBL30127850	0.81	L3MBTL1 (0.48)	KMT2AMASP2CFDMEN1PKM
	SCHEMBL28414767	0.81	PTGER4 (0.53)	KMT2AMASP2CFDMEN1PKM
	SCHEMBL2125378	0.81	SMN1; SMN2 (0.67)	KMT2AMEN1HTT
	SCHEMBL11337232	0.81	CFD (0.55)	KMT2AMASP2CFDMEN1PKM
	SCHEMBL2712814	0.81	KCNQ2 (0.59)	KMT2AMEN1KDM4ETDP1POLB
	SCHEMBL2711534	0.81	L3MBTL1 (0.58)	KMT2AMEN1HTT
	SCHEMBL4749159	0.81	DHODH (0.69)	KMT2AMASP2CFDMEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.