Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | ADA | P00813 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621417 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL18561534 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL29325152 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL18537397 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL3159103 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL12151832 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL12149492 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL12150864 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL18561536 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL21006620 | 1.00 | PDE3A (0.72) | PDE3APDE4DSLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 839 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4566670-A2 | MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS | Gilead Sciences, Inc. (US) | 2025-06-11 | — | — | EP | claimed |
| US-12083185-B2 | Small polymeric carriers for delivery of agents | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2024-09-10 | — | — | US | claimed |
| EP-4403221-A2 | MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS | Gilead Sciences, Inc. (US) | 2024-07-24 | — | — | EP | claimed |
| CN-118019981-A | Methods for characterizing tumors | 蒙彼利埃大学医疗中心 | 2024-05-10 | — | — | CN | claimed |
| CN-113054950-B | Relaxation oscillator and memory chip | 西安紫光国芯半导体有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-116726036-A | Application of NM107 in resisting infectious pancreatic necrosis virus | 中国水产科学研究院黑龙江水产研究所 | 2023-09-12 | — | — | CN | claimed |
| US-11021497-B2 | Compositions and methods for synthesis of phosphorylated molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-01 | — | — | US | claimed |
| US-20200385340-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | BIOTRON LTD (AU) | 2020-12-10 | — | — | US | claimed |
| US-10793924-B2 | Methods for detecting norovirus | QUEST DIAGNOSTICS INVESTMENTS LLC (US) | 2020-10-06 | — | — | US | claimed |
| US-20200239500-A1 | Compositions and Methods for Synthesis of Phosphorylated Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-07-30 | — | — | US | claimed |
| US-20070161611-A1 | POLYCYCLIC PHENOLIC COMPOUNDS AND USE IN TREATING VIRAL INFECTIONS | MIGENIX CORPORATION | 2007-07-12 | — | — | US | claimed |
| WO-2007062528-A1 | POLYCYCLIC PHENOLIC COMPOUNDS AND USE IN TREATING VIRAL INFECTIONS | MIGENIX CORPORATION (US) | 2007-06-07 | — | — | WO | claimed |
| EP-1585529-A2 | PROCESS FOR THE PRODUCTION OF 2'-BRANCHED NUCLEOSIDES | Idenix (Cayman) Limited (KY) | 2005-10-19 | — | — | EP | claimed |
| EP-1539188-A2 | NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE | Merck & Co., Inc. (US) | 2005-06-15 | — | — | EP | claimed |
| US-20050020825-A1 | Process for the production of 2'-branched nucleosides | IDENIX PHARMACEUTICALS LLC | 2005-01-27 | — | — | US | claimed |
| US-20040259934-A1 | Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds | OLSEN DAVID B (US) | 2004-12-23 | — | — | US | claimed |
| WO-2004052899-A2 | PROCESS FOR THE PRODUCTION OF 2'-BRANCHED NUCLEOSIDES | IDENIX (CAYMAN) LIMITED (KY) | 2004-06-24 | — | — | WO | claimed |
| US-20040110717-A1 | Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase | MERCK SHARP & DOHME LLC | 2004-06-10 | — | — | US | claimed |
| US-20040059104-A1 | Nucleotide mimics and their prodrugs | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2004-03-25 | — | — | US | claimed |
| WO-2002057425-A2 | NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE | MERCK & CO., INC. (US) | 2002-07-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239500-A1 | Compositions and Methods for Synthesis of Phosphorylated Molecules | PIK3CA, CHAMP1, TYMP | PDE3A 2076/4885PDE4D 1088/4885SLC29A1 498/4885 |
| US-20040110717-A1 | Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase | NSUN2, NSUN3, POLRMT | PDE3A 1235/4885PDE4D 996/4885SLC29A1 118/4885 |
| US-20040259934-A1 | Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds | SARS1, ACE, ACE2 | PDE3A 1769/4885PDE4D 3152/4885SLC29A1 19/4885 |
| US-12083185-B2 | Small polymeric carriers for delivery of agents | CD44, PGF, SLC46A1 | PDE3A 2485/4885PDE4D 2909/4885SLC29A1 552/4885 |
| US-11021497-B2 | Compositions and methods for synthesis of phosphorylated molecules | PIK3CA, CHAMP1, TYMP | PDE3A 2076/4885PDE4D 1088/4885SLC29A1 498/4885 |
| US-20070161611-A1 | POLYCYCLIC PHENOLIC COMPOUNDS AND USE IN TREATING VIRAL INFECTIONS | ACE, NCOA1, ACE2 | PDE3A 4181/4885PDE4D 4462/4885SLC29A1 2181/4885 |
| US-20040059104-A1 | Nucleotide mimics and their prodrugs | NUDT14, ENTPD5, MTAP | PDE3A 765/4885PDE4D 212/4885SLC29A1 19/4885 |
| US-20050020825-A1 | Process for the production of 2'-branched nucleosides | RNGTT, MTAP, NSUN2 | PDE3A 1307/4885PDE4D 312/4885SLC29A1 152/4885 |
| US-20200385340-A1 | HEPATITIS C ANTIVIRAL COMPOSITIONS AND METHODS | HAVCR2, HCCS, EIF2AK2 | PDE3A 602/4885PDE4D 2375/4885SLC29A1 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.