SCHEMBL1410139

SCHEMBL1410139

O=C(O)CC[C@H]1CC[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)O1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.41
▸ FFAR4 Q5NUL3 5/20 0.38
▸ FFAR1 O14842 4/20 0.38
▸ RXRA P19793 3/20 0.35
▸ RXRB P28702 3/20 0.35
▸ RXRG P48443 3/20 0.35
▸ SLC6A2 P23975 2/20 0.35
▸ SLC6A4 P31645 2/20 0.35
▸ SLC6A3 Q01959 2/20 0.35
▸ GPR17 Q13304 1/20 0.34
▸ CES2 O00748 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ TACR1 P25103 1/20 0.34
▸ RORC P51449 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1410779 1.00 LMNA (0.41) LMNAFFAR4FFAR1RXRARXRB
SCHEMBL1410337 1.00 LMNA (0.41) LMNAFFAR4FFAR1RXRARXRB
SCHEMBL1410366 0.92 FFAR1 (0.47) LMNAFFAR4FFAR1RXRARXRB
Tromethamine SCHEMBL1410570 0.92 LMNA (0.36) LMNAFFAR4FFAR1RXRARXRB
SCHEMBL1410504 0.88 RXRA (0.42) FFAR4FFAR1RXRARXRBRXRG
SCHEMBL1410689 0.87 FFAR4 (0.44) LMNAFFAR4FFAR1RXRARXRB
SCHEMBL1409539 0.87 FFAR1 (0.47) FFAR4FFAR1SLC6A2SLC6A4SLC6A3
SCHEMBL1410134 0.84 ALDH1A1 (0.38) SLC6A2SLC6A4SLC6A3RORC
SCHEMBL1410421 0.82 PTGIR (0.38) LMNAFFAR4FFAR1RXRARXRB
SCHEMBL12209968 0.78 SLC6A2 (0.58) SLC6A2SLC6A4SLC6A3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO INC (US) 2025-07-31 — — US claimed
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 — — CN claimed
EP-4507566-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION Belite Bio, Inc (US) 2025-02-19 — — EP claimed
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC 2024-07-25 — — US claimed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 — — EP claimed
CN-117440774-A Biomarkers of age-related macular degeneration 倍亮生物有限责任公司 2024-01-23 — — CN claimed
WO-2023200766-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO, INC (US) 2023-10-19 — — WO claimed
WO-2022246238-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC (US) 2022-11-24 — — WO claimed
EP-2295406-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL (JP) 2014-04-23 — — EP claimed
US-8338622-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-12-25 — — US claimed
US-20110251187-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-10-13 — — US claimed
EP-2295406-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2011-03-16 — — EP claimed
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO INC (US) 2025-07-31 — — US disclosed
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 — — CN disclosed
EP-4507566-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION Belite Bio, Inc (US) 2025-02-19 — — EP disclosed
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC 2024-07-25 — — US disclosed
US-20110251187-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-10-13 — — US disclosed
US-20110251187-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-10-13 — — US disclosed
US-20110251187-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-10-13 — — US disclosed
EP-2295406-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2011-03-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION PDE6C, SERPINA6, PDE6H LMNA 2480/4885FFAR4 1891/4885FFAR1 2722/4885
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION AGER, RBP4, RBP1 LMNA 1007/4885FFAR4 3691/4885FFAR1 3653/4885
US-20110251187-A1 HETEROCYCLIC COMPOUND NES, BMI1, DOT1L LMNA 2590/4885FFAR4 4589/4885FFAR1 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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