Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618157 | 0.88 | RPS6KA3 (0.84) | RPS6KA3TSHRGLASLC9A1MAPT | |
| SCHEMBL2494163 | 0.83 | RPS6KA3 (0.77) | RPS6KA3TSHRGLASLC9A1KMT2A | |
| SCHEMBL22375107 | 0.81 | RPS6KA3 (1.00) | RPS6KA3SLC9A1KMT2AKDM4EMAPT | |
| SCHEMBL3342201 | 0.81 | RPS6KA3 (0.73) | RPS6KA3SLC9A1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL2490946 | 0.81 | RPS6KA3 (0.73) | RPS6KA3SLC9A1KMT2AMAPTALDH1A1 | |
| SCHEMBL2491190 | 0.77 | RPS6KA3 (0.68) | RPS6KA3TSHRSLC9A1KMT2AKDM4E | |
| SCHEMBL31267895 | 0.77 | RPS6KA3 (0.68) | RPS6KA3TSHRSLC9A1KMT2AKDM4E | |
| SCHEMBL7813053 | 0.76 | RPS6KA3 (0.70) | RPS6KA3KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL27890010 | 0.75 | RPS6KA3 (0.64) | RPS6KA3SLC9A1KMT2AMAPTALDH1A1 | |
| SCHEMBL3403852 | 0.74 | SLC9A1 (0.63) | RPS6KA3TSHRGLASLC9A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102688233-B | Benzotriazole Derivative is as the synthesis of RSK2 inhibitor and application | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-102688233-A | Synthesis of benzotriazol derivative as RSK2 inhibitor and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-09-26 | — | — | CN | disclosed |