Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107042 | 0.81 | GHSR (0.38) | GHSRALDH1A1HTTRECQLPTGES2 | |
| SCHEMBL14106930 | 0.78 | DYRK1A (0.37) | ALDH1A1HTR6KDM4ELMNA | |
| SCHEMBL14107045 | 0.74 | HTR6 (0.50) | HTR6 | |
| SCHEMBL5103748 | 0.72 | HTR6 (0.48) | GHSRALDH1A1HTTRECQLHTR6 | |
| SCHEMBL5097122 | 0.71 | GHSR (0.39) | GHSRALDH1A1HTTRECQLPTGES2 | |
| SCHEMBL14106926 | 0.69 | ALDH1A1 (0.37) | ALDH1A1HTR6KDM4ELMNA | |
| SCHEMBL13403843 | 0.68 | ALDH1A1 (0.42) | GHSRALDH1A1HTTRECQLPTGES2 | |
| SCHEMBL5097211 | 0.68 | HTR6 (0.50) | GHSRALDH1A1HTTRECQLHTR6 | |
| SCHEMBL14106941 | 0.68 | HTR6 (0.54) | HTR6DRD3 | |
| SCHEMBL5103449 | 0.67 | GHSR (0.41) | GHSRALDH1A1HTTRECQLPTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101247-A2 | 6 ' SUBSTITUTED INDOLE AND INDAZOLE DERIVATIVES HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-08-21 | — | — | WO | disclosed |