Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 10/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14106929 | 0.78 | GHSR (0.38) | HTR6ALDH1A1KDM4ELMNA | |
| SCHEMBL14107045 | 0.76 | HTR6 (0.50) | HTR6 | |
| SCHEMBL14106941 | 0.72 | HTR6 (0.54) | HTR6MAPT | |
| SCHEMBL14106926 | 0.71 | ALDH1A1 (0.37) | HTR6ALDH1A1KDM4ELMNACHRNB2 | |
| SCHEMBL5095016 | 0.71 | HTR6 (0.53) | HTR6 | |
| SCHEMBL5103843 | 0.70 | CHRM1 (0.41) | DYRK1AHTR6ALDH1A1KDM4ELMNA | |
| SCHEMBL2548093 | 0.69 | DYRK1A (0.58) | DYRK1AHTR6 | |
| SCHEMBL29509780 | 0.69 | DYRK1A (0.58) | DYRK1AHTR6 | |
| SCHEMBL5095075 | 0.64 | HTR6 (0.53) | HTR6 | |
| SCHEMBL15515355 | 0.63 | PHGDH (0.47) | DYRK1AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101247-A2 | 6 ' SUBSTITUTED INDOLE AND INDAZOLE DERIVATIVES HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-08-21 | — | — | WO | disclosed |