Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672789 | 0.82 | ALDH1A1 (0.56) | EGFRL3MBTL1SRCNPSR1ALDH1A1 | |
| SCHEMBL29524438 | 0.82 | ALDH1A1 (0.56) | EGFRL3MBTL1SRCNPSR1ALDH1A1 | |
| SCHEMBL9038399 | 0.77 | CCR2 (0.51) | EGFRL3MBTL1SRCNPSR1CCR2 | |
| SCHEMBL9272720 | 0.76 | CCR2 (0.50) | EGFRL3MBTL1SRCNPSR1CCR2 | |
| SCHEMBL27854511 | 0.75 | MAPK1 (0.46) | L3MBTL1CCR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL27854540 | 0.74 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL4863785 | 0.72 | NPC1 (0.40) | L3MBTL1NPSR1ALDH1A1MAPTKDM4E | |
| SCHEMBL27854524 | 0.71 | FEN1 (0.55) | L3MBTL1NPSR1ALDH1A1MAPTKDM4E | |
| SCHEMBL27957963 | 0.71 | AGTR1 (0.62) | EGFRL3MBTL1SRCNPSR1ALDH1A1 | |
| SCHEMBL23411790 | 0.71 | EGFR (0.59) | EGFRSRCNPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012164085-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-12-06 | — | — | WO | disclosed |