SCHEMBL1413396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26912673	0.94	MAPT (0.59)	ALDH1A1KDM4EMAPTTHRBLMNA
	SCHEMBL6407264	0.87	LMNA (0.51)	ALDH1A1KDM4EMAPTLMNAKMT2A
	SCHEMBL2782013	0.84	LMNA (0.51)	KDM4EMAPTLMNAKMT2ACYP2D6
	SCHEMBL1413377	0.82	HTT (0.54)	ALDH1A1KDM4EMAPTLMNAKMT2A
	Hydrochloric Acid SCHEMBL11852231	0.81	JAK2 (0.55)	KDM4EMAPTLMNAKMT2ACYP2D6
	SCHEMBL1442314	0.81	HTR6 (0.63)	ALDH1A1KDM4ELMNACYP2D6CYP1A2
	SCHEMBL7548171	0.79	BCHE (0.44)	KDM4ELMNACYP2D6L3MBTL1DRD2
	SCHEMBL1413397	0.79	HTR6 (0.56)	KDM4ELMNAL3MBTL1CYP3A4PDGFRB
	SCHEMBL9703840	0.78	ADRB1 (0.69)	MAPTKMT2ADRD2
	SCHEMBL21047718	0.78	BCHE (0.42)	ALDH1A1KDM4EMAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.