Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182726 | 0.91 | ROCK2 (0.44) | MAOBMAOAMEN1MAPTKMT2A | |
| SCHEMBL14182840 | 0.90 | HDAC6 (0.45) | MAOBMAOAMAPTRAB9AHDAC6 | |
| SCHEMBL14182719 | 0.88 | MAOA (0.52) | MAOBMAOAKDM4EMEN1MAPT | |
| SCHEMBL14182776 | 0.88 | PTPN1 (0.46) | MAOBMAOAMEN1MAPTKMT2A | |
| SCHEMBL14182837 | 0.87 | RAB9A (0.44) | MAOBMAOAMEN1MAPTKMT2A | |
| SCHEMBL14182735 | 0.87 | MAOA (0.52) | MAOBMAOAMEN1MAPTKMT2A | |
| SCHEMBL14182724 | 0.87 | MAOA (0.52) | MAOBMAOAMEN1MAPTKMT2A | |
| SCHEMBL14182713 | 0.87 | MAOB (0.56) | MAOBMAOAKDM4EMEN1MAPT | |
| SCHEMBL14182765 | 0.86 | KCNQ2 (0.53) | MAOBMAOAKDM4EMEN1MAPT | |
| SCHEMBL14182745 | 0.86 | NAMPT (0.44) | MAOBMAOAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |