Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572563 | 0.83 | MAPT (1.00) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL648371 | 0.81 | L3MBTL1 (0.69) | MAPTHSD17B10ALDH1A1TSHRKMT2A | |
| SCHEMBL2478066 | 0.81 | KDM4E (0.56) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL2149614 | 0.80 | MAPT (0.71) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL28485370 | 0.79 | MAPT (0.59) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| Phenylaspirinate SCHEMBL29389369 | 0.78 | HSD17B10 (0.75) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| Phenylaspirinate SCHEMBL25954 | 0.78 | HSD17B10 (0.75) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL4731724 | 0.78 | LMNA (0.51) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL5710896 | 0.78 | HSD17B10 (0.64) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL1282647 | 0.78 | HSD17B10 (0.64) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081914-A1 | PROCESS FOR THE PREPARATION OF BENZO [D] ISOXAZOL-3-YL-METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF | DIPHARMA S.P.A. (IT) | 2008-04-03 | — | — | US | disclosed |
| US-7291742-B2 | Process for the preparation of benzo [d] isoxazol-3-yl-methanesulfonic acid and the intermediates thereof | DIPHARMA S.P.A. (IT) | 2007-11-06 | — | — | US | disclosed |
| US-7291742-B2 | Process for the preparation of benzo [d] isoxazol-3-yl-methanesulfonic acid and the intermediates thereof | DIPHARMA S.P.A. (IT) | 2007-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081914-A1 | PROCESS FOR THE PREPARATION OF BENZO [D] ISOXAZOL-3-YL-METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF | GABRD, GABRA5, GABRA6 | MAPT 2095/4885CYP1A2 83/4885CYP2C9 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.