Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201435 | 0.90 | TRPA1 (0.49) | SMN1; SMN2TRPA1GRM2GRM3 | |
| SCHEMBL14145254 | 0.78 | GRIK1 (0.47) | SMN1; SMN2HIF1ATRPA1MMP2GRM2 | |
| SCHEMBL4737745 | 0.78 | GRIK1 (0.47) | SMN1; SMN2HIF1ATRPA1MMP2GRM2 | |
| SCHEMBL14201456 | 0.78 | TSHR (0.45) | SMN1; SMN2HIF1AANPEPERAP1ERAP2 | |
| SCHEMBL14145649 | 0.77 | ALDH1A1 (0.42) | SMN1; SMN2ANPEPERAP1ERAP2METAP2 | |
| SCHEMBL7268813 | 0.77 | CES1 (0.44) | SMN1; SMN2ANPEPERAP1ERAP2CNR2 | |
| SCHEMBL16419905 | 0.73 | TSHR (0.47) | SMN1; SMN2CNR2TSHRTRPA1DPP4 | |
| SCHEMBL6720239 | 0.73 | LMNA (0.40) | SMN1; SMN2HIF1AGRM2GRM3 | |
| SCHEMBL8067994 | 0.73 | SLC6A2 (0.45) | SMN1; SMN2ANPEPERAP1ERAP2TSHR | |
| SCHEMBL837930 | 0.72 | MMP13 (0.47) | ANPEPERAP1ERAP2HPGDMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096799-A1 | COMPOUNDS FOR AND METHODS OF TREATING INSULIN RESISTANCE AND INFLAMMATION | FORBES MEDI-TECH (RESEARCH), INC. (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096799-A1 | COMPOUNDS FOR AND METHODS OF TREATING INSULIN RESISTANCE AND INFLAMMATION | PNLIP, CPT1A, CPT1B | SMN1; SMN2 1317/4885HIF1A 650/4885ANPEP 3029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.