Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | MAOA | P21397 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.58 |
| ▸ | ELANE | P08246 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | CTSG | P08311 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366938 | 0.95 | MAOA (0.68) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL140425 | 0.95 | MAOA (0.68) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL30361371 | 0.95 | MAOA (0.68) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL8505898 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL23723959 | 0.84 | FTO (0.73) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL11147739 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MAPTTDP1MAOAMAPK1 | |
| Danthron SCHEMBL28137084 | 0.83 | MAPT (0.91) | ALDH1A1MAPTTDP1TSHRMAOA | |
| Danthron SCHEMBL30544826 | 0.83 | MAPT (1.00) | ALDH1A1MAPTTDP1TSHRMAOA | |
| Danthron SCHEMBL29356886 | 0.83 | MAPT (1.00) | ALDH1A1MAPTTDP1TSHRMAOA | |
| Danthron SCHEMBL83688 | 0.83 | MAPT (1.00) | ALDH1A1MAPTTDP1TSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059067-A1 | 1-ACETYL-5-HYDROXYANTHRACENE-9,10-DIONE FOR TREATMENT OF RETINAL DISEASE | CHARLESSON, LLC (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120059067-A1 | 1-ACETYL-5-HYDROXYANTHRACENE-9,10-DIONE FOR TREATMENT OF RETINAL DISEASE | CHARLESSON, LLC (US) | 2012-03-08 | — | — | US | disclosed |
| US-8058316-B2 | STAT3 inhibiting compositions and methods | CHARLESSON, LLC (US) | 2011-11-15 | — | — | US | disclosed |
| US-8058316-B2 | STAT3 inhibiting compositions and methods | CHARLESSON, LLC (US) | 2011-11-15 | — | — | US | disclosed |
| US-20110077306-A1 | STAT3 INHIBITING COMPOSITIONS AND METHODS | CHARLESSON, LLC (US) | 2011-03-31 | — | — | US | disclosed |
| US-20110077306-A1 | STAT3 INHIBITING COMPOSITIONS AND METHODS | CHARLESSON, LLC (US) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077306-A1 | STAT3 INHIBITING COMPOSITIONS AND METHODS | STAT3, STAT1, STAT5B | ALDH1A1 1563/4885MAPT 669/4885TDP1 3879/4885 |
| US-20120059067-A1 | 1-ACETYL-5-HYDROXYANTHRACENE-9,10-DIONE FOR TREATMENT OF RETINAL DISEASE | ACAT1, ACAT2, LCLAT1 | ALDH1A1 55/4885MAPT 65/4885TDP1 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.