Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | CLPP | Q16740 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882258 | 0.80 | ACHE (0.42) | SIGMAR1KMT2ACLPPMEN1NPC1 | |
| SCHEMBL461647 | 0.76 | SIGMAR1 (0.47) | SIGMAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14211674 | 0.76 | SIGMAR1 (0.47) | SIGMAR1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL14211672 | 0.76 | SIGMAR1 (0.47) | SIGMAR1KMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL17632564 | 0.75 | SIGMAR1 (0.46) | SIGMAR1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL14211676 | 0.73 | FAAH (0.41) | SIGMAR1KMT2ACLPPMEN1NPC1 | |
| SCHEMBL2313255 | 0.73 | KDM4E (0.67) | SIGMAR1LMNAGAAKDM4ESMN1; SMN2 | |
| SCHEMBL14211678 | 0.70 | SIGMAR1 (0.50) | SIGMAR1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL14211699 | 0.70 | SIGMAR1 (0.50) | SIGMAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL30448278 | 0.69 | L3MBTL1 (0.54) | SIGMAR1KDM4EKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080086006-A1 | Process for Making Substituted Piperidines | MERCK SHARP & DOHME CORP. | 2008-04-10 | — | — | US | disclosed |
| US-20080086006-A1 | Process for Making Substituted Piperidines | MERCK SHARP & DOHME CORP. | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080086006-A1 | Process for Making Substituted Piperidines | ITPA, PAICS, PPIP5K2 | SIGMAR1 966/4885LMNA 3875/4885GAA 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.