Guanosine

Guanosine

SCHEMBL1421810

C[C@H](O)[C@@H](O)[C@@H](O)[C@@H](C=O)OP(=O)(O)OP(=O)(O)O.Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.55
NT5E P21589 1/20 0.54
FUT5 Q11128 1/20 0.52
KRAS P01116 4/20 0.51
HINT1 P49773 3/20 0.51
IMPDH2 P12268 3/20 0.50
HPGD P15428 1/20 0.50
IMPDH1 P20839 1/20 0.48
P2RY2 P41231 1/20 0.48
P2RY4 P51582 1/20 0.48
P2RY6 Q15077 1/20 0.48
DCPS Q96C86 1/20 0.47
GSK3A P49840 2/20 0.47
RPS6KA3 P51812 2/20 0.47
MAPK14 Q16539 2/20 0.47
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanosine SCHEMBL8429254 0.93 TGM2 (0.55) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL3264840 0.93 TGM2 (0.55) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL4816737 0.93 TGM2 (0.55) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL8425223 0.89 NT5E (0.58) TGM2NT5EFUT5KRASHINT1
SCHEMBL1697432 0.89 NT5E (0.61) TGM2NT5EFUT5KRASHINT1
SCHEMBL6027526 0.89 NT5E (0.61) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL30589987 0.87 NT5E (0.69) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL9827513 0.87 NT5E (0.69) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL6066347 0.87 NT5E (0.69) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL30125158 0.86 NT5E (0.68) TGM2NT5EFUT5KRASHINT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020261-A Method for total synthesis of N-glycan 中国科学院上海药物研究所 2025-05-20 CN claimed
US-20250115867-A1 AUGMENTATION OF CELL THERAPY EFFICACY INCLUDING TREATMENT WITH ALPHA, 1,3 FUCOSYLTRANSFERASE TARGAZYME INC (US) 2025-04-10 US claimed
US-20240418701-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE NANJING UNIVERSITY (CN) 2024-12-19 US claimed
US-20240271093-A1 AUGMENTATION OF CELL THERAPY EFFICACY INCLUDING TREATMENT WITH ALPHA 1,3 FUCOSYLTRANSFERASE TARGAZYME INC (US) 2024-08-15 US claimed
EP-4413379-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE Nanjing University (CN) 2024-08-14 EP claimed
CN-118103711-A Single molecule identification with reactive heterogeneous nanopores 南京大学 2024-05-28 CN claimed
US-11976298-B2 Augmentation of cell therapy efficacy including treatment with alpha 1,3 fucosyltransferase Targazyme, Inc. (US) 2024-05-07 US claimed
CN-117683833-A Method for preparing nucleotide sugar from nucleoside monophosphate 山东大学 2024-03-12 CN claimed
US-20230416681-A9 Augmentation of Cell Therapy Efficacy Including Treatment with Alpha 1,3 Fucosyltransferase TARGAZYME INC (US) 2023-12-28 US claimed
CN-112662604-B Recombinant escherichia coli for synthesizing 3-fucosyllactose and construction method thereof 量子高科(广东)生物有限公司 2023-10-20 CN claimed
WO-2007047654-A2 SPECIFIC ACCEPTORS FOR TRANFERASES TO SACCHARIDES AND METHOD FOR OBTAINING AND USING SAME HEALTH RESEARCH, INC. (US) 2007-04-26 WO claimed
EP-0816503-B1 ALPHA-1-6 FUCOSYLTRANSFERASES TOYO BOSEKI (JP) 2006-07-05 EP claimed
EP-1194168-A2 METHODS AND PRODUCTS FOR MANIPULATING UNCOUPLING PROTEIN EXPRESSION UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2002-04-10 EP claimed
US-6187754-B1 Sialyl-Lewisa and sialyl-Lewisx epitode analogues GLYCOTECH CORP. 2001-02-13 US claimed
WO-2000078941-A2 METHODS AND PRODUCTS FOR MANIPULATING UNCOUPLING PROTEIN EXPRESSION UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2000-12-28 WO claimed
US-5888777-A Process for the complete removal of protective groups on nucleoside diphosphate and triphosphate sugars with acetylesterase NOVARTIS AG (CH) 1999-03-30 US claimed
EP-0886639-A1 SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES GlycoTech Corp. (US) 1998-12-30 EP claimed
EP-0801684-A1 PROCESS FOR THE COMPLETE REMOVAL OF PROTECTIVE GROUPS ON NUCLEOSIDE DIPHOSPHATE AND TRIPHOSPHATE SUGARS Novartis AG (CH) 1997-10-22 EP claimed
WO-1997028174-A1 SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES NOVARTIS AG (CH) 1997-08-07 WO claimed
WO-1996024683-A1 PROCESS FOR THE COMPLETE REMOVAL OF PROTECTIVE GROUPS ON NUCLEOSIDE DIPHOSPHATE AND TRIPHOSPHATE SUGARS NOVARTIS AG (CH) 1996-08-15 WO claimed