Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.87 |
| ▸ | MMP9 | P14780 | 9/20 | 0.87 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.87 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.77 |
| ▸ | MMP1 | P03956 | 1/20 | 0.77 |
| ▸ | MMP3 | P08254 | 1/20 | 0.77 |
| ▸ | MMP7 | P09237 | 1/20 | 0.77 |
| ▸ | MMP13 | P45452 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533971 | 1.00 | MMP2 (0.87) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL6545297 | 0.93 | MMP2 (1.00) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL32691761 | 0.93 | MMP2 (1.00) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL1920507 | 0.93 | MMP2 (1.00) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL14218257 | 0.87 | MMP2 (0.87) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL4422501 | 0.87 | MMP2 (1.00) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL4422490 | 0.87 | MMP2 (1.00) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL14191416 | 0.87 | MMP9 (0.84) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL4188026 | 0.86 | MMP2 (0.85) | MMP2MMP9ADAMTS4ADAMTS5MMP1 | |
| SCHEMBL697591 | 0.86 | MMP2 (0.85) | MMP2MMP9ADAMTS4ADAMTS5MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119513-A1 | Sulfonamide Derivative Selectively Inhibiting Mmp-13 | SHIONOGI & CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119513-A1 | Sulfonamide Derivative Selectively Inhibiting Mmp-13 | MMP13, MMP3, MMP11 | MMP2 10/4885MMP9 7/4885ADAMTS4 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.