SCHEMBL14218550

SCHEMBL14218550

CC1(C)CC2N(C(=O)c3cccc4[nH]ccc34)CC2(C)C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.45
CCR5 P51681 1/20 0.43
MAPK14 Q16539 1/20 0.42
LMNA P02545 2/20 0.39
MGLL Q99685 2/20 0.39
DHPS P49366 1/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37
TUBA3E Q6PEY2 1/20 0.37
TUBA1A Q71U36 1/20 0.37
TUBA1C Q9BQE3 1/20 0.37
TUBB6 Q9BUF5 1/20 0.37
TUBB2B Q9BVA1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1094220 0.82 LMNA (0.60) LMNAAVPR2AVPR1A
SCHEMBL14218452 0.76 CNR2 (0.44) CNR2TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL14218514 0.76 NR4A2 (0.45) CNR2LMNAAVPR1A
SCHEMBL14218585 0.75 F7 (0.48) HDAC1
SCHEMBL14218479 0.73 NR4A2 (0.50) LMNA
SCHEMBL14218551 0.72 MEN1 (0.45) CNR2CCR5HCRTR2HDAC1
SCHEMBL14218480 0.72 NR3C1 (0.40) CNR2AVPR2AVPR1A
SCHEMBL14218510 0.71 CNR2 (0.43) CNR2CCR5MAPK14LMNAMGLL
SCHEMBL13127698 0.70 LMNA (0.47) LMNAAVPR2AVPR1A
SCHEMBL14218513 0.70 HPGD (0.45) LMNAHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080108598-A1 Pharmaceutical use of substituted amides NOVO NORDISK A/S (DK) 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080108598-A1 Pharmaceutical use of substituted amides HSD11B1, HSD3B1, HSD11B2 CNR2 1206/4885CCR5 3843/4885MAPK14 1300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.