Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HPGDS | O60760 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 5/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.51 |
| ▸ | AKT1 | P31749 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | NEK4 | P51957 | 2/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.51 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064333 | 0.90 | ANPEP (0.45) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL401005 | 0.87 | HPGDS (0.54) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL401441 | 0.87 | HPGDS (0.54) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL14196095 | 0.86 | — | — | |
| SCHEMBL1912263 | 0.82 | ADAMTS5 (0.50) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL1109199 | 0.82 | CYP26A1 (0.59) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL1109400 | 0.81 | CTSB (0.47) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL2101266 | 0.81 | CTSS (0.64) | CTSBCTSSCTSKL3MBTL1CTSL | |
| SCHEMBL1912184 | 0.79 | HDAC1 (0.53) | — | |
| SCHEMBL1109112 | 0.78 | CTSL (0.50) | CTSBCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |