SCHEMBL401441

SCHEMBL401441

NC[C@H](NC(=O)c1ccc(-c2ccccc2)cc1)C(=O)NO

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 2/20 0.54
CTSB P07858 3/20 0.53
RPS6KA5 O75582 2/20 0.52
AKT1 P31749 2/20 0.52
GSK3B P49841 2/20 0.52
NEK4 P51957 2/20 0.52
PRKCD Q05655 2/20 0.52
PRKG2 Q13237 2/20 0.52
ROCK1 Q13464 2/20 0.52
PRKG1 Q13976 2/20 0.52
PKN2 Q16513 2/20 0.52
CLK4 Q9HAZ1 2/20 0.52
MAPK13 O15264 1/20 0.52
DYRK3 O43781 1/20 0.52
ROCK2 O75116 1/20 0.52
PRKD3 O94806 1/20 0.52
MAP4K4 O95819 1/20 0.52
CHEK2 O96017 1/20 0.52
PRKCG P05129 1/20 0.52
CDK1 P06493 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL401005 1.00 HPGDS (0.54) HPGDSCTSBRPS6KA5AKT1GSK3B
SCHEMBL1109400 0.95 CTSB (0.47) HPGDSCTSBRPS6KA5AKT1GSK3B
SCHEMBL7462967 0.92 CTSL (0.50) CTSBCTSSCTSKHDAC3HDAC4
SCHEMBL27518156 0.92 CTSL (0.50) CTSBCTSSCTSKHDAC3HDAC4
SCHEMBL1109112 0.92 CTSL (0.50) CTSBCTSSCTSKHDAC3HDAC4
SCHEMBL10286213 0.90 HDAC8 (0.58) HPGDSCTSBCTSSCTSKL3MBTL1
SCHEMBL1109185 0.90 CTSB (0.43) HPGDSCTSBRPS6KA5AKT1GSK3B
SCHEMBL29534040 0.90 OGG1 (0.49) HPGDSCTSBRPS6KA5AKT1GSK3B
SCHEMBL1109484 0.90 ANPEP (0.50) HPGDSCTSBRPS6KA5AKT1GSK3B
SCHEMBL12064333 0.88 ANPEP (0.45) HPGDSCTSBNPC1RAB9ACTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-219533640-U 24 hour display clock 郑宏志 2023-08-15 CN disclosed
CN-115572770-B Method for judging genetic relationship through SNP mismatch rate 上海蓝沙生物科技有限公司 2023-06-30 CN disclosed
CN-115572770-A Method for judging genetic relationship through SNP (single nucleotide polymorphism) mismatch rate 上海蓝沙生物科技有限公司 2023-01-06 CN disclosed
US-8153843-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2012-04-10 US disclosed
US-8153843-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2012-04-10 US disclosed
US-8153843-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2012-04-10 US disclosed
US-8101640-B2 Antibacterial agents NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2012-01-24 US disclosed
US-8101640-B2 Antibacterial agents NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2012-01-24 US disclosed
US-8084615-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2011-12-27 US disclosed
US-8084615-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2011-12-27 US disclosed
US-20090163496-A1 ANTIBACTERIAL AGENTS UNIVERSITY OF WASHINGTON (US) 2009-06-25 US disclosed
US-20090163496-A1 ANTIBACTERIAL AGENTS UNIVERSITY OF WASHINGTON (US) 2009-06-25 US disclosed
US-20080269221-A1 ANTIBACTERIAL AGENTS NOVARTIS VACCINES AND DIAGNOSTICS, INC. 2008-10-30 US disclosed
US-20080269221-A1 ANTIBACTERIAL AGENTS NOVARTIS VACCINES AND DIAGNOSTICS, INC. 2008-10-30 US disclosed
US-7358359-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2008-04-15 US disclosed
US-7358359-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2008-04-15 US disclosed
US-7358359-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2008-04-15 US disclosed
US-20070244197-A1 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2007-10-18 US disclosed
US-20070244197-A1 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2007-10-18 US disclosed
US-20060154988-A1 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2006-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244197-A1 Antibacterial agents MRPL21, SI, PGLS HPGDS 253/4885CTSB 259/4885RPS6KA5 332/4885
US-20080269221-A1 ANTIBACTERIAL AGENTS MRPL21, SI, PGLS HPGDS 253/4885CTSB 259/4885RPS6KA5 332/4885
US-20060154988-A1 Antibacterial agents MRPL21, SI, PGLS HPGDS 253/4885CTSB 259/4885RPS6KA5 332/4885
US-20090163496-A1 ANTIBACTERIAL AGENTS MRPL21, SI, PGLS HPGDS 253/4885CTSB 259/4885RPS6KA5 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.