Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Methyl Phosphonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | GABBR2 | O75899 | 5/20 | 0.55 |
| ▸ | GABBR1 | Q9UBS5 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Phosphonate SCHEMBL2535355 | 1.00 | — | — | |
| Methyl Phosphonate SCHEMBL7997206 | 1.00 | CA2 (0.61) | CA2GABBR2GABBR1CYP1A2TSHR | |
| Methyl Phosphonate SCHEMBL8005468 | 1.00 | CA2 (0.61) | CA2GABBR2GABBR1CYP1A2TSHR | |
| Ethylenediamine SCHEMBL27865483 | 0.92 | — | — | |
| Methyl Phosphonate SCHEMBL7997367 | 0.86 | GABBR2 (0.65) | CA2GABBR2GABBR1CYP1A2TSHR | |
| Methyl Phosphonate SCHEMBL8007917 | 0.86 | TSHR (0.53) | CA2GABBR2GABBR1CYP1A2TSHR | |
| Methyl Phosphonate SCHEMBL28529800 | 0.86 | — | — | |
| Methyl Phosphonate SCHEMBL27690941 | 0.85 | GABBR2 (0.46) | CA2GABBR2GABBR1CYP1A2TSHR | |
| Phosphoric Acid SCHEMBL16701801 | 0.84 | ALDH1A1 (0.56) | GABBR2GABBR1CYP1A2TSHRTHPO | |
| Phosphoric Acid SCHEMBL1978724 | 0.84 | ALDH1A1 (0.56) | GABBR2GABBR1CYP1A2TSHRTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118325402-A | Scale inhibition slurry and preparation method and application thereof | 箭牌家居集团股份有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-117888108-A | Molybdenum aluminum etching solution and preparation method thereof | 易安爱富(武汉)科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-116854061-A | Potassium dihydrogen phosphate mother liquor recovery treatment process | 诸城市浩天药业有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-115386927-A | Method for plating rhodium and ruthenium on surface of copper material | 惠州市安泰普表面处理科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| EP-2669407-B1 | Galvanic baths for obtaining a low-carat gold alloy, and galvanic process that uses said baths | BLUCLAD S P A (IT) | 2022-03-30 | — | — | EP | claimed |
| EP-1969025-B1 | CLEAR AND THICKENING AQUEOUS COMPOSITIONS, THE USE THEREOF IN ACIDIC AQUEOUS FORMULATIONS, AND THE RESULTING FORMULATIONS | COATEX SAS (FR) | 2018-02-21 | — | — | EP | claimed |
| EP-2414477-A1 | TEMPERATURE ADJUSTMENT DEVICE | E. I. du Pont de Nemours and Company (US) | 2012-02-08 | — | — | EP | claimed |
| US-20110172450-A1 | METHODS AND APPARATUS FOR PRODUCING ALKYL ESTERS FROM LIPID FEED STOCKS AND SYSTEMS INCLUDING SAME | MCNEFF RESEARCH CONSULTANTS, INC. | 2011-07-14 | — | — | US | claimed |
| US-7897798-B2 | Methods and apparatus for producing alkyl esters from lipid feed stocks and systems including same | MCNEFF RESEARCH CONSULTANTS, INC. (US) | 2011-03-01 | — | — | US | claimed |
| WO-2010117833-A1 | TEMPERATURE ADJUSTMENT DEVICE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-14 | — | — | WO | claimed |
| EP-1703000-A1 | CHROME-FREE PASSIVATING SOLUTION | China International Marine Containers (Group) Co., Ltd. (CN) | 2006-09-20 | — | — | EP | claimed |
| US-7018612-B1 | Method of preparing a radioactive rhenium complex solution | MALLINCKRODT INC. (US) | 2006-03-28 | — | — | US | claimed |
| EP-0210043-B1 | CONTRAST AGENT FOR NMR SCANNING | GUERBET S.A. (FR) | 1992-01-08 | — | — | EP | claimed |
| US-4880007-A | AMINO DI- OR POLYPHOSPHONATE-PARAMAGNETIC METAL ION COMPLEX | AMERSHAM INTERNATIONAL PLC (GB) | 1989-11-14 | — | — | US | claimed |
| EP-0126921-B1 | BATH FOR THE GALVANIC DEPOSITION OF GOLD ALLOYS | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | claimed |
| EP-0276518-A1 | Lead immersion bath and method of supplificially exchanging a tin layer for a lead layer | Koninklijke Philips Electronics N.V. (NL) | 1988-08-03 | — | — | EP | claimed |
| US-H325-H | Electroless deposition of transition metals | RICHARDSON CHEMICAL COMPANY | 1987-09-01 | — | — | US | claimed |
| EP-0210043-A2 | Contrast agent for NMR scanning | GUERBET S.A. (FR) | 1987-01-28 | — | — | EP | claimed |
| US-4332692-A | REMOVAL OF OILY SOILS FROM FABRICS | THE PROCTER & GAMBLE COMPANY (US) | 1982-06-01 | — | — | US | claimed |
| US-4059678-A | Stabilization of iron-containing acidic hydrogen peroxide solutions | FMC CORPORATION (US) | 1977-11-22 | — | — | US | claimed |