Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Methyl Phosphonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Phosphonate SCHEMBL142377 | 1.00 | CA2 (0.61) | — | |
| Methyl Phosphonate SCHEMBL7997206 | 1.00 | CA2 (0.61) | — | |
| Methyl Phosphonate SCHEMBL8005468 | 1.00 | CA2 (0.61) | — | |
| Ethylenediamine SCHEMBL27865483 | 0.92 | — | — | |
| Methyl Phosphonate SCHEMBL7997367 | 0.86 | GABBR2 (0.65) | — | |
| Methyl Phosphonate SCHEMBL8007917 | 0.86 | TSHR (0.53) | — | |
| Methyl Phosphonate SCHEMBL28529800 | 0.86 | — | — | |
| Methyl Phosphonate SCHEMBL27690941 | 0.85 | GABBR2 (0.46) | — | |
| Phosphoric Acid SCHEMBL16701801 | 0.84 | ALDH1A1 (0.56) | — | |
| Phosphoric Acid SCHEMBL1978724 | 0.84 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194482-B1 | USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS FOR PLASTICS, FLAME-RETARDANT PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS | FRAUNHOFER GES FORSCHUNG (DE) | 2024-05-08 | — | — | EP | claimed |
| CN-107075202-B | Use of organooxyimide salts as flame retardants, flame-retardant plastic compositions, method for the production thereof and moulded parts, paints or coatings | 弗劳恩霍弗应用研究促进协会 | 2020-06-16 | — | — | CN | claimed |
| EP-3083849-B1 | GREENHOUSE ARRANGEMENT | RKW SE (DE) | 2019-10-02 | — | — | EP | claimed |
| EP-3194486-B1 | USE OF ORGANIC OXYIMIDE SALTS AS FLAMERETARDANTS; FLAMERETARDANT PLASTIC COMPOSITIONS; PROCESS TO PRODUCE SAID COMPOSITIONS AND MOULDINGS, PAINTS OR COATINGS | FRAUNHOFER GES FORSCHUNG (DE) | 2019-04-24 | — | — | EP | claimed |
| EP-3155041-B1 | USE OF HYDROXYBENZOTRIAZOLE DERIVATIVES AND/OR HYDROXY INDAZOLE DERIVATIVES AS FLAME RETARDANTS FOR PLASTICS AND FLAMEPROOF PLASTIC MOULDED BODIES | FRAUNHOFER GES FORSCHUNG (DE) | 2018-03-21 | — | — | EP | claimed |
| CN-106661270-A | Use of hydroxybenzotriazole derivatives and/or hydroxy indazole derivatives as flame retardants for plastics and flameproof plastic moulded bodies | 弗劳恩霍夫应用研究促进协会 | 2017-05-10 | — | — | CN | claimed |
| US-20160309663-A1 | GREENHOUSE ARRANGEMENT | RKW SE (DE) | 2016-10-27 | — | — | US | claimed |
| EP-3083849-A1 | GREENHOUSE ARRANGEMENT | RKW SE (DE) | 2016-10-26 | — | — | EP | claimed |
| WO-2015090548-A1 | GREENHOUSE ARRANGEMENT | RKW SE (DE) | 2015-06-25 | — | — | WO | claimed |
| EP-3194482-B1 | USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS FOR PLASTICS, FLAME-RETARDANT PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS | FRAUNHOFER GES FORSCHUNG (DE) | 2024-05-08 | — | — | EP | disclosed |
| CN-107001698-B | Use of phosphorus-containing organooxyimides as flame retardants for plastics, flame-retardant plastic compositions, and method for the production thereof | 弗劳恩霍弗应用研究促进协会 | 2020-05-26 | — | — | CN | disclosed |
| US-10544284-B2 | Use of phosphorous-containing organic oxyimides as flame retardants and/or as stabilizers for plastics, flame-retardant and/or stabilized plastic compositions, method for the production thereof, moulded part, paint and coatings | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2020-01-28 | — | — | US | disclosed |
| EP-3083849-B1 | GREENHOUSE ARRANGEMENT | RKW SE (DE) | 2019-10-02 | — | — | EP | disclosed |
| US-10323136-B2 | Use of hydroxybenzotriazole derivatives and/or hydroxy indazole derivatives as flame retardants for plastics and flameproof plastic moulded bodies | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2019-06-18 | — | — | US | disclosed |
| WO-2016042038-A1 | USE OF ORGANIC OXYIMIDES AS RADICAL GENERATORS IN PLASTICS, METHOD FOR GENERATING RADICALS IN PLASTICS AND USE OF SAID METHOD | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-03-24 | — | — | WO | disclosed |
| WO-2015090548-A1 | GREENHOUSE ARRANGEMENT | RKW SE (DE) | 2015-06-25 | — | — | WO | disclosed |
| US-8853307-B2 | Flame-retardant composition comprising a phosphonic acid derivative | THOR GMBH (DE) | 2014-10-07 | — | — | US | disclosed |
| US-20140005289-A1 | FLAME-RETARDANT COMPOSITION COMPRISING A PHOSPHONIC ACID DERIVATIVE | THOR GMBH (DE) | 2014-01-02 | — | — | US | disclosed |
| US-8349925-B2 | Flame-retardant composition comprising a phosphonic acid derivative | THOR GMBH (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20110257310-A1 | FLAME-RETARDANT COMPOSITION COMPRISING A PHOSPHONIC ACID DERIVATIVE | THOR GMBH (DE) | 2011-10-20 | — | — | US | disclosed |