Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14245573 | 0.92 | FFAR1 (0.38) | PPARGACHEFFAR1AKR1B1 | |
| SCHEMBL14245549 | 0.90 | FFAR1 (0.43) | FFAR1AKR1B1 | |
| SCHEMBL14246017 | 0.89 | DPP4 (0.40) | ACHEFFAR1AKR1B1 | |
| SCHEMBL9846009 | 0.88 | SQOR (0.46) | — | |
| SCHEMBL14246157 | 0.86 | ALDH1A1 (0.40) | ACHEFFAR1AKR1B1 | |
| SCHEMBL9846003 | 0.86 | PPARG (0.40) | PPARGACHEFFAR1AKR1B1 | |
| SCHEMBL14246069 | 0.85 | ACHE (0.41) | ACHE | |
| SCHEMBL14245333 | 0.85 | PPARG (0.39) | PPARGACHEFFAR1AKR1B1 | |
| SCHEMBL14245058 | 0.85 | FFAR1 (0.40) | PPARGACHEFFAR1AKR1B1 | |
| SCHEMBL14245434 | 0.85 | FFAR1 (0.46) | ACHEFFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120322819-A1 | COMPOUND CONTAINING A NOVEL 4-ALKOXYPYRIMIDINE STRUCTURE AND MEDICINE CONTAINING SAME | KOWA COMPANY, LTD. (JP) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322819-A1 | COMPOUND CONTAINING A NOVEL 4-ALKOXYPYRIMIDINE STRUCTURE AND MEDICINE CONTAINING SAME | AGTR2, AGTR1, GPR119 | PPARG 4/4885NPC1 3025/4885RAB9A 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.