Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NPM1 | P06748 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247592 | 0.75 | HCAR1 (0.47) | MEN1KMT2AGAAMAPK14CSNK1A1 | |
| SCHEMBL14247366 | 0.74 | ALDH1A1 (0.47) | MEN1KMT2AMAPK14ADORA2AADORA1 | |
| SCHEMBL4755701 | 0.72 | MEN1 (1.00) | MEN1KMT2AMAP4K4GAACYP11B1 | |
| SCHEMBL7306716 | 0.72 | ADORA2A (0.45) | MEN1KMT2AGAAADORA2AADORA1 | |
| SCHEMBL14247710 | 0.72 | PI4KA (0.49) | — | |
| SCHEMBL14247826 | 0.71 | DHFR (0.46) | — | |
| SCHEMBL7165172 | 0.71 | NOS2 (0.49) | MEN1KMT2AMAPK14ADORA2AADORA1 | |
| SCHEMBL14247782 | 0.70 | NCF1 (0.46) | MEN1KMT2A | |
| SCHEMBL14247504 | 0.68 | HCAR1 (0.49) | MEN1KMT2AGAAADORA2AADORA1 | |
| SCHEMBL2158739 | 0.67 | KMT2A (0.75) | MEN1KMT2AMAP4K4GAACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |