Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424922 | 0.81 | LMNA (0.60) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL13678671 | 0.80 | LMNA (0.66) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL441997 | 0.80 | LMNA (0.66) | ST6GAL1LMNATHRBMTORMDM2 | |
| Hydrochloric Acid SCHEMBL11852550 | 0.79 | LMNA (0.65) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL16131588 | 0.79 | ST6GAL1 (0.40) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL1525218 | 0.78 | ALDH1A1 (0.56) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL7158886 | 0.77 | ST6GAL1 (0.40) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL7157425 | 0.77 | NT5E (0.40) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL28197797 | 0.77 | LMNA (0.55) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL10510561 | 0.77 | HRAS (0.44) | ST6GAL1LMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10655127-B2 | RNA amidates and thioamidates for RNAi | GERON CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180119147-A1 | Rna Amidates and Thioamidates for Rnai | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2018-05-03 | — | — | US | disclosed |
| US-9822360-B2 | RNA amidates and thioamidates for RNAi | GERON CORPORATION (US) | 2017-11-21 | — | — | US | disclosed |
| US-20160130580-A1 | RNA AMIDATES AND THIOAMIDATES FOR RNAI | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2016-05-12 | — | — | US | disclosed |
| US-9133233-B2 | RNA amidates and thioamidates for RNAi | GERON CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| EP-1694842-B1 | RNA AMIDATES AND THIOAMIDATES FOR RNAI | GERON CORP (US) | 2011-03-23 | — | — | EP | disclosed |
| US-20070275919-A1 | Rna Amidates and Thioamidates for Rnai | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10655127-B2 | RNA amidates and thioamidates for RNAi | NSUN3, RNGTT, RNMT | ST6GAL1 2478/4885LMNA 3962/4885THRB 2568/4885 |
| US-20070275919-A1 | Rna Amidates and Thioamidates for Rnai | NSUN3, RNGTT, RNMT | ST6GAL1 2478/4885LMNA 3962/4885THRB 2568/4885 |
| US-20180119147-A1 | Rna Amidates and Thioamidates for Rnai | NSUN3, RNGTT, RNMT | ST6GAL1 2478/4885LMNA 3962/4885THRB 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.