Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14268044 | 0.83 | NCF1 (0.45) | NCF1ADRB2ARGRM4PTGDR2 | |
| SCHEMBL14259401 | 0.81 | NCF1 (0.41) | NCF1ADRB2ARGRM4PTGDR2 | |
| SCHEMBL4244849 | 0.77 | RORC (0.43) | NCF1ADRB2ARPTGDR2NPC1 | |
| SCHEMBL14259404 | 0.76 | SLC6A2 (0.48) | SLC6A2GRM4 | |
| SCHEMBL4239994 | 0.76 | NR4A2 (0.60) | MAPT | |
| SCHEMBL28419807 | 0.75 | SLC6A2 (0.45) | SLC6A2NPC1MAPT | |
| Hydrochloric Acid SCHEMBL4242731 | 0.75 | ADRB2 (0.39) | NCF1ADRB2ARPTGDR2NPC1 | |
| SCHEMBL8170195 | 0.74 | ATP4A (0.48) | SLC6A2MAPT | |
| SCHEMBL26998342 | 0.74 | NCF1 (0.46) | NCF1ADRB2ARGRM4PTGDR2 | |
| SCHEMBL6344740 | 0.74 | PTGDR2 (0.48) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2008-03-13 | — | — | US | disclosed |
| EP-1897875-A1 | Process for producing 1-pyridin-4-YL-indoles | Fujifilm Finechemicals Co. Ltd. (JP) | 2008-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064878-A1 | Low cost, high yield, industrial scale reaction of 4-halopyridine and indole derivatives in presence of strong organic base; heavy metal catalyst free | IDO1, IDO2, TDO2 | NCF1 3563/4885ADRB2 92/4885AR 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.