SCHEMBL14280260

SCHEMBL14280260

COc1ccc(C(C)N2C(=O)c3ccc4c5c(ccc(c35)C2=O)C(=O)N(C(C)c2ccc(OC)cc2)C4=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 2/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
HTT P42858 1/20 0.45
TNF P01375 1/20 0.45
ESR1 P03372 1/20 0.41
HPGD P15428 1/20 0.40
NPY1R P25929 1/20 0.40
NPY2R P49146 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TP53 P04637 1/20 0.40
HSD11B1 P28845 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 3/20 0.38
POLB P06746 1/20 0.38
ATM Q13315 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13890984 0.89 TNF (0.49) ALDH1A1MAPTKDM4ELMNAGAA
SCHEMBL16321910 0.87 TNF (0.58) ALDH1A1MAPTTNFHPGDNPY1R
SCHEMBL16321909 0.87 TNF (0.58) ALDH1A1MAPTTNFHPGDNPY1R
SCHEMBL13890985 0.81 L3MBTL1 (0.45) TNFHSD11B1L3MBTL1
SCHEMBL13878069 0.81 ALDH1A1 (0.41) ALDH1A1KDM4ELMNAHTTHSD11B1
SCHEMBL14280257 0.79 MET (0.40) LMNAHSD11B1POLB
SCHEMBL14280266 0.79 PTGES (0.42) HSD11B1KMT2APOLBATM
SCHEMBL14280264 0.79 POLB (0.55) ALDH1A1KDM4ELMNAGAAESR1
SCHEMBL14280267 0.79 DNMT3A (0.42) ALDH1A1KDM4ELMNAGAAHPGD
SCHEMBL13878053 0.79 ALDH1A1 (0.46) ALDH1A1MAPTKDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080014520-A1 Organic photoreceptor for short wavelengths and electrophotographic imaging forming apparatus employing the organic photoreceptor SAMSUNG ELECTRONICS CO., LTD. 2008-01-17 US disclosed
US-20080014520-A1 Organic photoreceptor for short wavelengths and electrophotographic imaging forming apparatus employing the organic photoreceptor SAMSUNG ELECTRONICS CO., LTD. 2008-01-17 US disclosed
EP-1879076-A2 Organic photoreceptor for short wavelengths and electrophotographic imaging forming apparatus employing the organic photoreceptor Samsung Electronics Co., Ltd. (KR) 2008-01-16 EP disclosed
US-7314692-B2 Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-01 US disclosed
US-7314692-B2 Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-01 US disclosed